Perfluoro-n-octane as a temporary intraocular tamponade in a staged approach to manage complex retinal detachments

Daniel Barthelmes, Jay Chandra Department of Ophthalmology, Westmead Hospital, Westmead, NSW, Australia Purpose: To evaluate outcomes in patients with complex retinal detachments (RD) with proliferative vitreoretinopathy (PVR) requiring retinectomy using a staged approach utilizing perfluoro-n-oc...

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Autores principales:	Barthelmes D, Chandra J
Formato:	article
Lenguaje:	EN
Publicado:	Dove Medical Press 2015
Materias:	Ophthalmology RE1-994
Acceso en línea:	https://doaj.org/article/371b0efa9c254124ab51ac9790b61cdf
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spelling	oai:doaj.org-article:371b0efa9c254124ab51ac9790b61cdf2021-12-02T05:04:42ZPerfluoro-n-octane as a temporary intraocular tamponade in a staged approach to manage complex retinal detachments1177-5483https://doaj.org/article/371b0efa9c254124ab51ac9790b61cdf2015-02-01T00:00:00Zhttp://www.dovepress.com/perfluoro-n-octane-as-a-temporary-intraocular-tamponade-in-a-staged-ap-peer-reviewed-article-OPTHhttps://doaj.org/toc/1177-5483 Daniel Barthelmes, Jay Chandra Department of Ophthalmology, Westmead Hospital, Westmead, NSW, Australia Purpose: To evaluate outcomes in patients with complex retinal detachments (RD) with proliferative vitreoretinopathy (PVR) requiring retinectomy using a staged approach utilizing perfluoro-n-octane (PFO) as a short-term postoperative intraocular tamponade.Methods: Retrospective analysis. Patients who underwent 23G pars plana vitrectomy for the management of complicated RD where PFO was used as a primary temporary intraocular tamponade. Only eyes with PVR in rhegmatogenous RD or eyes with penetrating injuries or globe ruptures (ocular trauma) and subsequent RD with PVR were included. Analysis of 17 eyes of 17 consecutive patients with a minimum follow-up of 12 months during a period of 5 years. The primary outcome measure was the reattachment rate after at least 12 months of follow-up after the PFO removal. Secondary outcome measures were changes in visual acuity, complications due to PFO use, and necessity for further surgeries.Results: Eight eyes with prior penetrating injuries or globe rupture and nine eyes with rhegmatogenous pathology were included. All eyes had PFO as temporary tamponade for 14 days (median), which was replaced by silicon oil. Sixteen eyes (94%) had complete and one eye partial reattachment. No redetachments occurred. All eyes retained or improved visual acuity. On average, only 2.5 procedures, including silicon oil removal, were performed. Two eyes had long-term intraocular pressure of 5 mmHg and no eye had intraocular pressure of ≥21 mmHg. No long-term inflammation was observed.Conclusion: PFO seems to be beneficial in a staged approach to repair complex detachments when used as short-term tamponade. A median period of 14 days allowed for both sufficient retinal support plus a reduction in side effects seen in long-term endotamponades. Keywords: pars plana vitrectomy, complex retinal detachments, proliferative vitreoretinopathy, traumaBarthelmes DChandra JDove Medical PressarticleOphthalmologyRE1-994ENClinical Ophthalmology, Vol 2015, Iss default, Pp 413-418 (2015)
institution	DOAJ
collection	DOAJ
language	EN
topic	Ophthalmology RE1-994
spellingShingle	Ophthalmology RE1-994 Barthelmes D Chandra J Perfluoro-n-octane as a temporary intraocular tamponade in a staged approach to manage complex retinal detachments
description	Daniel Barthelmes, Jay Chandra Department of Ophthalmology, Westmead Hospital, Westmead, NSW, Australia Purpose: To evaluate outcomes in patients with complex retinal detachments (RD) with proliferative vitreoretinopathy (PVR) requiring retinectomy using a staged approach utilizing perfluoro-n-octane (PFO) as a short-term postoperative intraocular tamponade.Methods: Retrospective analysis. Patients who underwent 23G pars plana vitrectomy for the management of complicated RD where PFO was used as a primary temporary intraocular tamponade. Only eyes with PVR in rhegmatogenous RD or eyes with penetrating injuries or globe ruptures (ocular trauma) and subsequent RD with PVR were included. Analysis of 17 eyes of 17 consecutive patients with a minimum follow-up of 12 months during a period of 5 years. The primary outcome measure was the reattachment rate after at least 12 months of follow-up after the PFO removal. Secondary outcome measures were changes in visual acuity, complications due to PFO use, and necessity for further surgeries.Results: Eight eyes with prior penetrating injuries or globe rupture and nine eyes with rhegmatogenous pathology were included. All eyes had PFO as temporary tamponade for 14 days (median), which was replaced by silicon oil. Sixteen eyes (94%) had complete and one eye partial reattachment. No redetachments occurred. All eyes retained or improved visual acuity. On average, only 2.5 procedures, including silicon oil removal, were performed. Two eyes had long-term intraocular pressure of 5 mmHg and no eye had intraocular pressure of ≥21 mmHg. No long-term inflammation was observed.Conclusion: PFO seems to be beneficial in a staged approach to repair complex detachments when used as short-term tamponade. A median period of 14 days allowed for both sufficient retinal support plus a reduction in side effects seen in long-term endotamponades. Keywords: pars plana vitrectomy, complex retinal detachments, proliferative vitreoretinopathy, trauma
format	article
author	Barthelmes D Chandra J
author_facet	Barthelmes D Chandra J
author_sort	Barthelmes D
title	Perfluoro-n-octane as a temporary intraocular tamponade in a staged approach to manage complex retinal detachments
title_short	Perfluoro-n-octane as a temporary intraocular tamponade in a staged approach to manage complex retinal detachments
title_full	Perfluoro-n-octane as a temporary intraocular tamponade in a staged approach to manage complex retinal detachments
title_fullStr	Perfluoro-n-octane as a temporary intraocular tamponade in a staged approach to manage complex retinal detachments
title_full_unstemmed	Perfluoro-n-octane as a temporary intraocular tamponade in a staged approach to manage complex retinal detachments
title_sort	perfluoro-n-octane as a temporary intraocular tamponade in a staged approach to manage complex retinal detachments
publisher	Dove Medical Press
publishDate	2015
url	https://doaj.org/article/371b0efa9c254124ab51ac9790b61cdf
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Perfluoro-n-octane as a temporary intraocular tamponade in a staged approach to manage complex retinal detachments

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