The end-joining factor Ku acts in the end-resection of double strand break-free arrested replication forks

The end-joining factor Ku acts in the end-resection of double strand break-free arrested replication forks

Terminally arrested replication forks are restarted through homologous recombination after processing single-stranded DNA gaps. Here the authors show that resection is regulated by the NHEJ factor Ku, helping to fine-tune recombination at forks.

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Autores principales: Ana Teixeira-Silva, Anissia Ait Saada, Julien Hardy, Ismail Iraqui, Marina Charlotte Nocente, Karine Fréon, Sarah A. E. Lambert
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2017
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Acceso en línea:https://doaj.org/article/3726da4e581049a5bdae9cbe92ff1eda
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spelling oai:doaj.org-article:3726da4e581049a5bdae9cbe92ff1eda2021-12-02T13:24:23ZThe end-joining factor Ku acts in the end-resection of double strand break-free arrested replication forks10.1038/s41467-017-02144-52041-1723https://doaj.org/article/3726da4e581049a5bdae9cbe92ff1eda2017-12-01T00:00:00Zhttps://doi.org/10.1038/s41467-017-02144-5https://doaj.org/toc/2041-1723Terminally arrested replication forks are restarted through homologous recombination after processing single-stranded DNA gaps. Here the authors show that resection is regulated by the NHEJ factor Ku, helping to fine-tune recombination at forks.Ana Teixeira-SilvaAnissia Ait SaadaJulien HardyIsmail IraquiMarina Charlotte NocenteKarine FréonSarah A. E. LambertNature PortfolioarticleScienceQENNature Communications, Vol 8, Iss 1, Pp 1-14 (2017)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Ana Teixeira-Silva
Anissia Ait Saada
Julien Hardy
Ismail Iraqui
Marina Charlotte Nocente
Karine Fréon
Sarah A. E. Lambert
The end-joining factor Ku acts in the end-resection of double strand break-free arrested replication forks
description Terminally arrested replication forks are restarted through homologous recombination after processing single-stranded DNA gaps. Here the authors show that resection is regulated by the NHEJ factor Ku, helping to fine-tune recombination at forks.
format article
author Ana Teixeira-Silva
Anissia Ait Saada
Julien Hardy
Ismail Iraqui
Marina Charlotte Nocente
Karine Fréon
Sarah A. E. Lambert
author_facet Ana Teixeira-Silva
Anissia Ait Saada
Julien Hardy
Ismail Iraqui
Marina Charlotte Nocente
Karine Fréon
Sarah A. E. Lambert
author_sort Ana Teixeira-Silva
title The end-joining factor Ku acts in the end-resection of double strand break-free arrested replication forks
title_short The end-joining factor Ku acts in the end-resection of double strand break-free arrested replication forks
title_full The end-joining factor Ku acts in the end-resection of double strand break-free arrested replication forks
title_fullStr The end-joining factor Ku acts in the end-resection of double strand break-free arrested replication forks
title_full_unstemmed The end-joining factor Ku acts in the end-resection of double strand break-free arrested replication forks
title_sort end-joining factor ku acts in the end-resection of double strand break-free arrested replication forks
publisher Nature Portfolio
publishDate 2017
url https://doaj.org/article/3726da4e581049a5bdae9cbe92ff1eda
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