The end-joining factor Ku acts in the end-resection of double strand break-free arrested replication forks
Terminally arrested replication forks are restarted through homologous recombination after processing single-stranded DNA gaps. Here the authors show that resection is regulated by the NHEJ factor Ku, helping to fine-tune recombination at forks.
Saved in:
Main Authors: | Ana Teixeira-Silva, Anissia Ait Saada, Julien Hardy, Ismail Iraqui, Marina Charlotte Nocente, Karine Fréon, Sarah A. E. Lambert |
---|---|
Format: | article |
Language: | EN |
Published: |
Nature Portfolio
2017
|
Subjects: | |
Online Access: | https://doaj.org/article/3726da4e581049a5bdae9cbe92ff1eda |
Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
Similar Items
-
PAXX promotes KU accumulation at DNA breaks and is essential for end-joining in XLF-deficient mice
by: Xiangyu Liu, et al.
Published: (2017) -
Coordinated nuclease activities counteract Ku at single-ended DNA double-strand breaks
by: Pauline Chanut, et al.
Published: (2016) -
Correction: Corrigendum: Coordinated nuclease activities counteract Ku at single-ended DNA double-strand breaks
by: Pauline Chanut, et al.
Published: (2017) -
Essential factors for incompatible DNA end joining at chromosomal DNA double strand breaks in vivo.
by: Hideaki Ogiwara, et al.
Published: (2011) -
The nuclear pore primes recombination-dependent DNA synthesis at arrested forks by promoting SUMO removal
by: Karol Kramarz, et al.
Published: (2020)