Potential Applications of Nanomaterials and Technology for Diabetic Wound Healing

Que Bai,1,* Kai Han,1,* Kai Dong,1 Caiyun Zheng,1 Yanni Zhang,1 Qianfa Long,2 Tingli Lu1 1School of Life Sciences, Northwestern Polytechnical University, Xi’an, Shaanxi 710072, People’s Republic of China; 2Mini-Invasive Neurosurgery and Translational Medical Center, Xi’...

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Autores principales:	Bai Q, Han K, Dong K, Zheng C, Zhang Y, Long Q, Lu T
Formato:	article
Lenguaje:	EN
Publicado:	Dove Medical Press 2020
Materias:	hydrogels nanoparticles nanotechnology diabetic wound healing Medicine (General) R5-920
Acceso en línea:	https://doaj.org/article/37341300eda94358a252b4bb464f85c6
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spelling	oai:doaj.org-article:37341300eda94358a252b4bb464f85c62021-12-02T13:48:41ZPotential Applications of Nanomaterials and Technology for Diabetic Wound Healing1178-2013https://doaj.org/article/37341300eda94358a252b4bb464f85c62020-12-01T00:00:00Zhttps://www.dovepress.com/potential-applications-of-nanomaterials-and-technology-for-diabetic-wo-peer-reviewed-article-IJNhttps://doaj.org/toc/1178-2013Que Bai,1,* Kai Han,1,* Kai Dong,1 Caiyun Zheng,1 Yanni Zhang,1 Qianfa Long,2 Tingli Lu1 1School of Life Sciences, Northwestern Polytechnical University, Xi’an, Shaanxi 710072, People’s Republic of China; 2Mini-Invasive Neurosurgery and Translational Medical Center, Xi’an Central Hospital, Xi’an Jiaotong University, Xi’an 710003, People’s Republic of China*These authors contributed equally to this workCorrespondence: Qianfa Long; Tingli Lu Tel +86 029-88460332Email lonva@live.cn; lutinglixinxin@nwpu.edu.cnAbstract: Diabetic wound shows delayed and incomplete healing processes, which in turn exposes patients to an environment with a high risk of infection. This article has summarized current developments of nanoparticles/hydrogels and nanotechnology used for promoting the wound healing process in either diabetic animal models or patients with diabetes mellitus. These nanoparticles/hydrogels promote diabetic wound healing by loading bioactive molecules (such as growth factors, genes, proteins/peptides, stem cells/exosomes, etc.) and non-bioactive substances (metal ions, oxygen, nitric oxide, etc.). Among them, smart hydrogels (a very promising method for loading many types of bioactive components) are currently favored by researchers. In addition, nanoparticles/hydrogels can be combined with some technology (including PTT, LBL self-assembly technique and 3D-printing technology) to treat diabetic wound repair. By reviewing the recent literatures, we also proposed new strategies for improving multifunctional treatment of diabetic wounds in the future.Keywords: hydrogels, nanoparticles, nanotechnology, diabetic wound healingBai QHan KDong KZheng CZhang YLong QLu TDove Medical Pressarticlehydrogelsnanoparticlesnanotechnologydiabetic wound healingMedicine (General)R5-920ENInternational Journal of Nanomedicine, Vol Volume 15, Pp 9717-9743 (2020)
institution	DOAJ
collection	DOAJ
language	EN
topic	hydrogels nanoparticles nanotechnology diabetic wound healing Medicine (General) R5-920
spellingShingle	hydrogels nanoparticles nanotechnology diabetic wound healing Medicine (General) R5-920 Bai Q Han K Dong K Zheng C Zhang Y Long Q Lu T Potential Applications of Nanomaterials and Technology for Diabetic Wound Healing
description	Que Bai,1,* Kai Han,1,* Kai Dong,1 Caiyun Zheng,1 Yanni Zhang,1 Qianfa Long,2 Tingli Lu1 1School of Life Sciences, Northwestern Polytechnical University, Xi’an, Shaanxi 710072, People’s Republic of China; 2Mini-Invasive Neurosurgery and Translational Medical Center, Xi’an Central Hospital, Xi’an Jiaotong University, Xi’an 710003, People’s Republic of China*These authors contributed equally to this workCorrespondence: Qianfa Long; Tingli Lu Tel +86 029-88460332Email lonva@live.cn; lutinglixinxin@nwpu.edu.cnAbstract: Diabetic wound shows delayed and incomplete healing processes, which in turn exposes patients to an environment with a high risk of infection. This article has summarized current developments of nanoparticles/hydrogels and nanotechnology used for promoting the wound healing process in either diabetic animal models or patients with diabetes mellitus. These nanoparticles/hydrogels promote diabetic wound healing by loading bioactive molecules (such as growth factors, genes, proteins/peptides, stem cells/exosomes, etc.) and non-bioactive substances (metal ions, oxygen, nitric oxide, etc.). Among them, smart hydrogels (a very promising method for loading many types of bioactive components) are currently favored by researchers. In addition, nanoparticles/hydrogels can be combined with some technology (including PTT, LBL self-assembly technique and 3D-printing technology) to treat diabetic wound repair. By reviewing the recent literatures, we also proposed new strategies for improving multifunctional treatment of diabetic wounds in the future.Keywords: hydrogels, nanoparticles, nanotechnology, diabetic wound healing
format	article
author	Bai Q Han K Dong K Zheng C Zhang Y Long Q Lu T
author_facet	Bai Q Han K Dong K Zheng C Zhang Y Long Q Lu T
author_sort	Bai Q
title	Potential Applications of Nanomaterials and Technology for Diabetic Wound Healing
title_short	Potential Applications of Nanomaterials and Technology for Diabetic Wound Healing
title_full	Potential Applications of Nanomaterials and Technology for Diabetic Wound Healing
title_fullStr	Potential Applications of Nanomaterials and Technology for Diabetic Wound Healing
title_full_unstemmed	Potential Applications of Nanomaterials and Technology for Diabetic Wound Healing
title_sort	potential applications of nanomaterials and technology for diabetic wound healing
publisher	Dove Medical Press
publishDate	2020
url	https://doaj.org/article/37341300eda94358a252b4bb464f85c6
work_keys_str_mv	AT baiq potentialapplicationsofnanomaterialsandtechnologyfordiabeticwoundhealing AT hank potentialapplicationsofnanomaterialsandtechnologyfordiabeticwoundhealing AT dongk potentialapplicationsofnanomaterialsandtechnologyfordiabeticwoundhealing AT zhengc potentialapplicationsofnanomaterialsandtechnologyfordiabeticwoundhealing AT zhangy potentialapplicationsofnanomaterialsandtechnologyfordiabeticwoundhealing AT longq potentialapplicationsofnanomaterialsandtechnologyfordiabeticwoundhealing AT lut potentialapplicationsofnanomaterialsandtechnologyfordiabeticwoundhealing
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Potential Applications of Nanomaterials and Technology for Diabetic Wound Healing

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