Calmodulin dissociates the STIM1-Orai1 complex and STIM1 oligomers
Store-operated calcium entry (SOCE) is elicited by the interaction of oligomerized STIM1 with plasma membrane Orai channels. Here, the authors show that this process is regulated by calmodulin, which binds STIM1 and disassembles the STIM1-Orai1 complex and STIM1 oligomers.
Guardado en:
| Autores principales: | , , , , , , , , |
|---|---|
| Formato: | article |
| Lenguaje: | EN |
| Publicado: |
Nature Portfolio
2017
|
| Materias: | |
| Acceso en línea: | https://doaj.org/article/373f68a4cf084daebb80635140f0ff9a |
| Etiquetas: |
Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!
|
| Sumario: | Store-operated calcium entry (SOCE) is elicited by the interaction of oligomerized STIM1 with plasma membrane Orai channels. Here, the authors show that this process is regulated by calmodulin, which binds STIM1 and disassembles the STIM1-Orai1 complex and STIM1 oligomers. |
|---|