Calmodulin dissociates the STIM1-Orai1 complex and STIM1 oligomers

Store-operated calcium entry (SOCE) is elicited by the interaction of oligomerized STIM1 with plasma membrane Orai channels. Here, the authors show that this process is regulated by calmodulin, which binds STIM1 and disassembles the STIM1-Orai1 complex and STIM1 oligomers.

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Autores principales:	Xin Li, Guangyan Wu, Yin Yang, Shijuan Fu, Xiaofen Liu, Huimin Kang, Xue Yang, Xun-Cheng Su, Yuequan Shen
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2017
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/373f68a4cf084daebb80635140f0ff9a
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spelling	oai:doaj.org-article:373f68a4cf084daebb80635140f0ff9a2021-12-02T17:01:24ZCalmodulin dissociates the STIM1-Orai1 complex and STIM1 oligomers10.1038/s41467-017-01135-w2041-1723https://doaj.org/article/373f68a4cf084daebb80635140f0ff9a2017-10-01T00:00:00Zhttps://doi.org/10.1038/s41467-017-01135-whttps://doaj.org/toc/2041-1723Store-operated calcium entry (SOCE) is elicited by the interaction of oligomerized STIM1 with plasma membrane Orai channels. Here, the authors show that this process is regulated by calmodulin, which binds STIM1 and disassembles the STIM1-Orai1 complex and STIM1 oligomers.Xin LiGuangyan WuYin YangShijuan FuXiaofen LiuHuimin KangXue YangXun-Cheng SuYuequan ShenNature PortfolioarticleScienceQENNature Communications, Vol 8, Iss 1, Pp 1-14 (2017)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Xin Li Guangyan Wu Yin Yang Shijuan Fu Xiaofen Liu Huimin Kang Xue Yang Xun-Cheng Su Yuequan Shen Calmodulin dissociates the STIM1-Orai1 complex and STIM1 oligomers
description	Store-operated calcium entry (SOCE) is elicited by the interaction of oligomerized STIM1 with plasma membrane Orai channels. Here, the authors show that this process is regulated by calmodulin, which binds STIM1 and disassembles the STIM1-Orai1 complex and STIM1 oligomers.
format	article
author	Xin Li Guangyan Wu Yin Yang Shijuan Fu Xiaofen Liu Huimin Kang Xue Yang Xun-Cheng Su Yuequan Shen
author_facet	Xin Li Guangyan Wu Yin Yang Shijuan Fu Xiaofen Liu Huimin Kang Xue Yang Xun-Cheng Su Yuequan Shen
author_sort	Xin Li
title	Calmodulin dissociates the STIM1-Orai1 complex and STIM1 oligomers
title_short	Calmodulin dissociates the STIM1-Orai1 complex and STIM1 oligomers
title_full	Calmodulin dissociates the STIM1-Orai1 complex and STIM1 oligomers
title_fullStr	Calmodulin dissociates the STIM1-Orai1 complex and STIM1 oligomers
title_full_unstemmed	Calmodulin dissociates the STIM1-Orai1 complex and STIM1 oligomers
title_sort	calmodulin dissociates the stim1-orai1 complex and stim1 oligomers
publisher	Nature Portfolio
publishDate	2017
url	https://doaj.org/article/373f68a4cf084daebb80635140f0ff9a
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Calmodulin dissociates the STIM1-Orai1 complex and STIM1 oligomers

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