CRISPR/Cas9-based genetic screen of SCNT-reprogramming resistant genes identifies critical genes for male germ cell development in mice
Abstract Male germ cells undergo complex developmental processes eventually producing spermatozoa through spermatogenesis, although the molecular mechanisms remain largely elusive. We have previously identified somatic cell nuclear transfer-reprogramming resistant genes (SRRGs) that are highly enric...
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Autores principales: | Most Sumona Akter, Masashi Hada, Daiki Shikata, Gen Watanabe, Atsuo Ogura, Shogo Matoba |
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Formato: | article |
Lenguaje: | EN |
Publicado: |
Nature Portfolio
2021
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Materias: | |
Acceso en línea: | https://doaj.org/article/374cdb8ab5d348a38dd1a31ada6dd9d3 |
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