Interpretable dimensionality reduction of single cell transcriptome data with deep generative models

Although single-cell transcriptome data are increasingly available, their interpretation remains a challenge. Here, the authors present a dimensionality reduction approach that preserves both the local and global neighbourhood structures in the data thus enhancing its interpretability.

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Bibliographic Details
Main Authors: Jiarui Ding, Anne Condon, Sohrab P. Shah
Format: article
Language:EN
Published: Nature Portfolio 2018
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Online Access:https://doaj.org/article/374e2f7ee4b743cebc2a0022380ea83b
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