A tetravalent live attenuated dengue virus vaccine stimulates balanced immunity to multiple serotypes in humans

A tetravalent live attenuated dengue virus vaccine stimulates balanced immunity to multiple serotypes in humans

Multivalent vaccines that confer protection to multiple serotypes of Dengue virus have been established. Here the authors examine the presence of vaccine induced multivalent antibodies and how these link to protection in a human challenge model of Dengue virus.

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Autores principales: Usha K. Nivarthi, Jesica Swanstrom, Matthew J. Delacruz, Bhumi Patel, Anna P. Durbin, Steve S. Whitehead, Beth D. Kirkpatrick, Kristen K. Pierce, Sean A. Diehl, Leah Katzelnick, Ralph S. Baric, Aravinda M. de Silva
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2021
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Acceso en línea:https://doaj.org/article/3754cf1077b043a0a2eef363edc7666d
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spelling oai:doaj.org-article:3754cf1077b043a0a2eef363edc7666d2021-12-02T10:52:47ZA tetravalent live attenuated dengue virus vaccine stimulates balanced immunity to multiple serotypes in humans10.1038/s41467-021-21384-02041-1723https://doaj.org/article/3754cf1077b043a0a2eef363edc7666d2021-02-01T00:00:00Zhttps://doi.org/10.1038/s41467-021-21384-0https://doaj.org/toc/2041-1723Multivalent vaccines that confer protection to multiple serotypes of Dengue virus have been established. Here the authors examine the presence of vaccine induced multivalent antibodies and how these link to protection in a human challenge model of Dengue virus.Usha K. NivarthiJesica SwanstromMatthew J. DelacruzBhumi PatelAnna P. DurbinSteve S. WhiteheadBeth D. KirkpatrickKristen K. PierceSean A. DiehlLeah KatzelnickRalph S. BaricAravinda M. de SilvaNature PortfolioarticleScienceQENNature Communications, Vol 12, Iss 1, Pp 1-12 (2021)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Usha K. Nivarthi
Jesica Swanstrom
Matthew J. Delacruz
Bhumi Patel
Anna P. Durbin
Steve S. Whitehead
Beth D. Kirkpatrick
Kristen K. Pierce
Sean A. Diehl
Leah Katzelnick
Ralph S. Baric
Aravinda M. de Silva
A tetravalent live attenuated dengue virus vaccine stimulates balanced immunity to multiple serotypes in humans
description Multivalent vaccines that confer protection to multiple serotypes of Dengue virus have been established. Here the authors examine the presence of vaccine induced multivalent antibodies and how these link to protection in a human challenge model of Dengue virus.
format article
author Usha K. Nivarthi
Jesica Swanstrom
Matthew J. Delacruz
Bhumi Patel
Anna P. Durbin
Steve S. Whitehead
Beth D. Kirkpatrick
Kristen K. Pierce
Sean A. Diehl
Leah Katzelnick
Ralph S. Baric
Aravinda M. de Silva
author_facet Usha K. Nivarthi
Jesica Swanstrom
Matthew J. Delacruz
Bhumi Patel
Anna P. Durbin
Steve S. Whitehead
Beth D. Kirkpatrick
Kristen K. Pierce
Sean A. Diehl
Leah Katzelnick
Ralph S. Baric
Aravinda M. de Silva
author_sort Usha K. Nivarthi
title A tetravalent live attenuated dengue virus vaccine stimulates balanced immunity to multiple serotypes in humans
title_short A tetravalent live attenuated dengue virus vaccine stimulates balanced immunity to multiple serotypes in humans
title_full A tetravalent live attenuated dengue virus vaccine stimulates balanced immunity to multiple serotypes in humans
title_fullStr A tetravalent live attenuated dengue virus vaccine stimulates balanced immunity to multiple serotypes in humans
title_full_unstemmed A tetravalent live attenuated dengue virus vaccine stimulates balanced immunity to multiple serotypes in humans
title_sort tetravalent live attenuated dengue virus vaccine stimulates balanced immunity to multiple serotypes in humans
publisher Nature Portfolio
publishDate 2021
url https://doaj.org/article/3754cf1077b043a0a2eef363edc7666d
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