A somatic piRNA pathway in the Drosophila fat body ensures metabolic homeostasis and normal lifespan

The Piwi-interacting RNA (piRNA) pathway is known to suppress transposable elements in gonadal tissues. Here the authors provide evidence for a functional piRNA pathway in the somatic cells of theDrosophilafat body with roles in metabolism, immunological function and overall health.

Guardado en:

Detalles Bibliográficos
Autores principales:	Brian C. Jones, Jason G. Wood, Chengyi Chang, Austin D. Tam, Michael J. Franklin, Emily R. Siegel, Stephen L. Helfand
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2016
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/375810040fa843ed8187901066d6abbf
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!

id	oai:doaj.org-article:375810040fa843ed8187901066d6abbf
record_format	dspace
spelling	oai:doaj.org-article:375810040fa843ed8187901066d6abbf2021-12-02T17:31:18ZA somatic piRNA pathway in the Drosophila fat body ensures metabolic homeostasis and normal lifespan10.1038/ncomms138562041-1723https://doaj.org/article/375810040fa843ed8187901066d6abbf2016-12-01T00:00:00Zhttps://doi.org/10.1038/ncomms13856https://doaj.org/toc/2041-1723The Piwi-interacting RNA (piRNA) pathway is known to suppress transposable elements in gonadal tissues. Here the authors provide evidence for a functional piRNA pathway in the somatic cells of theDrosophilafat body with roles in metabolism, immunological function and overall health.Brian C. JonesJason G. WoodChengyi ChangAustin D. TamMichael J. FranklinEmily R. SiegelStephen L. HelfandNature PortfolioarticleScienceQENNature Communications, Vol 7, Iss 1, Pp 1-9 (2016)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Brian C. Jones Jason G. Wood Chengyi Chang Austin D. Tam Michael J. Franklin Emily R. Siegel Stephen L. Helfand A somatic piRNA pathway in the Drosophila fat body ensures metabolic homeostasis and normal lifespan
description	The Piwi-interacting RNA (piRNA) pathway is known to suppress transposable elements in gonadal tissues. Here the authors provide evidence for a functional piRNA pathway in the somatic cells of theDrosophilafat body with roles in metabolism, immunological function and overall health.
format	article
author	Brian C. Jones Jason G. Wood Chengyi Chang Austin D. Tam Michael J. Franklin Emily R. Siegel Stephen L. Helfand
author_facet	Brian C. Jones Jason G. Wood Chengyi Chang Austin D. Tam Michael J. Franklin Emily R. Siegel Stephen L. Helfand
author_sort	Brian C. Jones
title	A somatic piRNA pathway in the Drosophila fat body ensures metabolic homeostasis and normal lifespan
title_short	A somatic piRNA pathway in the Drosophila fat body ensures metabolic homeostasis and normal lifespan
title_full	A somatic piRNA pathway in the Drosophila fat body ensures metabolic homeostasis and normal lifespan
title_fullStr	A somatic piRNA pathway in the Drosophila fat body ensures metabolic homeostasis and normal lifespan
title_full_unstemmed	A somatic piRNA pathway in the Drosophila fat body ensures metabolic homeostasis and normal lifespan
title_sort	somatic pirna pathway in the drosophila fat body ensures metabolic homeostasis and normal lifespan
publisher	Nature Portfolio
publishDate	2016
url	https://doaj.org/article/375810040fa843ed8187901066d6abbf
work_keys_str_mv	AT briancjones asomaticpirnapathwayinthedrosophilafatbodyensuresmetabolichomeostasisandnormallifespan AT jasongwood asomaticpirnapathwayinthedrosophilafatbodyensuresmetabolichomeostasisandnormallifespan AT chengyichang asomaticpirnapathwayinthedrosophilafatbodyensuresmetabolichomeostasisandnormallifespan AT austindtam asomaticpirnapathwayinthedrosophilafatbodyensuresmetabolichomeostasisandnormallifespan AT michaeljfranklin asomaticpirnapathwayinthedrosophilafatbodyensuresmetabolichomeostasisandnormallifespan AT emilyrsiegel asomaticpirnapathwayinthedrosophilafatbodyensuresmetabolichomeostasisandnormallifespan AT stephenlhelfand asomaticpirnapathwayinthedrosophilafatbodyensuresmetabolichomeostasisandnormallifespan AT briancjones somaticpirnapathwayinthedrosophilafatbodyensuresmetabolichomeostasisandnormallifespan AT jasongwood somaticpirnapathwayinthedrosophilafatbodyensuresmetabolichomeostasisandnormallifespan AT chengyichang somaticpirnapathwayinthedrosophilafatbodyensuresmetabolichomeostasisandnormallifespan AT austindtam somaticpirnapathwayinthedrosophilafatbodyensuresmetabolichomeostasisandnormallifespan AT michaeljfranklin somaticpirnapathwayinthedrosophilafatbodyensuresmetabolichomeostasisandnormallifespan AT emilyrsiegel somaticpirnapathwayinthedrosophilafatbodyensuresmetabolichomeostasisandnormallifespan AT stephenlhelfand somaticpirnapathwayinthedrosophilafatbodyensuresmetabolichomeostasisandnormallifespan
_version_	1718380666413907968

A somatic piRNA pathway in the Drosophila fat body ensures metabolic homeostasis and normal lifespan

Ejemplares similares