A somatic piRNA pathway in the Drosophila fat body ensures metabolic homeostasis and normal lifespan

A somatic piRNA pathway in the Drosophila fat body ensures metabolic homeostasis and normal lifespan

The Piwi-interacting RNA (piRNA) pathway is known to suppress transposable elements in gonadal tissues. Here the authors provide evidence for a functional piRNA pathway in the somatic cells of theDrosophilafat body with roles in metabolism, immunological function and overall health.

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Autores principales: Brian C. Jones, Jason G. Wood, Chengyi Chang, Austin D. Tam, Michael J. Franklin, Emily R. Siegel, Stephen L. Helfand
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2016
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Science
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Acceso en línea:https://doaj.org/article/375810040fa843ed8187901066d6abbf
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