Maximum levels of cross‐contamination for 24 antimicrobial active substances in non‐target feed. Part 11: Sulfonamides

Abstract The specific concentrations of sulfonamides in non‐target feed for food‐producing animals, below which there would not be an effect on the emergence of, and/or selection for, resistance in bacteria relevant for human and animal health, as well as the specific antimicrobial concentrations in...

Descripción completa

Guardado en:

Detalles Bibliográficos
Autores principales:	EFSA Panel on Biological Hazards (BIOHAZ), Konstantinos Koutsoumanis, Ana Allende, Avelino Alvarez‐Ordóñez, Declan Bolton, Sara Bover‐Cid, Marianne Chemaly, Robert Davies, Alessandra De Cesare, Lieve Herman, Friederike Hilbert, Roland Lindqvist, Maarten Nauta, Giuseppe Ru, Marion Simmons, Panagiotis Skandamis, Elisabetta Suffredini, Dan I. Andersson, Vasileios Bampidis, Johan Bengtsson‐Palme, Damien Bouchard, Aude Ferran, Maryline Kouba, Secundino López Puente, Marta López‐Alonso, Søren Saxmose Nielsen, Alena Pechová, Mariana Petkova, Sebastien Girault, Alessandro Broglia, Beatriz Guerra, Matteo Lorenzo Innocenti, Ernesto Liébana, Gloria López‐Gálvez, Paola Manini, Pietro Stella, Luisa Peixe
Formato:	article
Lenguaje:	EN
Publicado:	Wiley 2021
Materias:	Sulfonamides antimicrobial resistance sub‐inhibitory concentration growth promotion yield increase food‐producing animals Nutrition. Foods and food supply TX341-641 Chemical technology TP1-1185
Acceso en línea:	https://doaj.org/article/375e5cf464314db79f4d372ed6c4e1eb
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!

id	oai:doaj.org-article:375e5cf464314db79f4d372ed6c4e1eb
record_format	dspace
spelling	oai:doaj.org-article:375e5cf464314db79f4d372ed6c4e1eb2021-11-23T08:30:51ZMaximum levels of cross‐contamination for 24 antimicrobial active substances in non‐target feed. Part 11: Sulfonamides1831-473210.2903/j.efsa.2021.6863https://doaj.org/article/375e5cf464314db79f4d372ed6c4e1eb2021-10-01T00:00:00Zhttps://doi.org/10.2903/j.efsa.2021.6863https://doaj.org/toc/1831-4732Abstract The specific concentrations of sulfonamides in non‐target feed for food‐producing animals, below which there would not be an effect on the emergence of, and/or selection for, resistance in bacteria relevant for human and animal health, as well as the specific antimicrobial concentrations in feed which have an effect in terms of growth promotion/increased yield were assessed by EFSA in collaboration with EMA. Details of the methodology used for this assessment, associated data gaps and uncertainties, are presented in a separate document. To address antimicrobial resistance, the Feed Antimicrobial Resistance Selection Concentration (FARSC) model developed specifically for the assessment was applied. However, due to the lack of data on the parameters required to calculate the FARSC, it was not possible to conclude the assessment until further experimental data are available. To address growth promotion, data from scientific publications obtained from an extensive literature review were used. Levels in feed that showed to have an effect on growth promotion/increased yield were identified for three sulfonamides: sulfamethazine, sulfathiazole and sulfamerazine. It was recommended to carry out studies to generate the data that are required to fill the gaps which prevented the calculation of the FARSC for these antimicrobials.EFSA Panel on Biological Hazards (BIOHAZ)Konstantinos KoutsoumanisAna AllendeAvelino Alvarez‐OrdóñezDeclan BoltonSara Bover‐CidMarianne ChemalyRobert DaviesAlessandra De CesareLieve HermanFriederike HilbertRoland LindqvistMaarten NautaGiuseppe RuMarion SimmonsPanagiotis SkandamisElisabetta SuffrediniDan I. AnderssonVasileios BampidisJohan Bengtsson‐PalmeDamien BouchardAude FerranMaryline KoubaSecundino López PuenteMarta López‐AlonsoSøren Saxmose NielsenAlena PechováMariana PetkovaSebastien GiraultAlessandro BrogliaBeatriz GuerraMatteo Lorenzo InnocentiErnesto LiébanaGloria López‐GálvezPaola ManiniPietro StellaLuisa PeixeWileyarticleSulfonamidesantimicrobial resistancesub‐inhibitory concentrationgrowth promotionyield increasefood‐producing animalsNutrition. Foods and food supplyTX341-641Chemical technologyTP1-1185ENEFSA Journal, Vol 19, Iss 10, Pp n/a-n/a (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Sulfonamides antimicrobial resistance sub‐inhibitory concentration growth promotion yield increase food‐producing animals Nutrition. Foods and food supply TX341-641 Chemical technology TP1-1185
spellingShingle	Sulfonamides antimicrobial resistance sub‐inhibitory concentration growth promotion yield increase food‐producing animals Nutrition. Foods and food supply TX341-641 Chemical technology TP1-1185 EFSA Panel on Biological Hazards (BIOHAZ) Konstantinos Koutsoumanis Ana Allende Avelino Alvarez‐Ordóñez Declan Bolton Sara Bover‐Cid Marianne Chemaly Robert Davies Alessandra De Cesare Lieve Herman Friederike Hilbert Roland Lindqvist Maarten Nauta Giuseppe Ru Marion Simmons Panagiotis Skandamis Elisabetta Suffredini Dan I. Andersson Vasileios Bampidis Johan Bengtsson‐Palme Damien Bouchard Aude Ferran Maryline Kouba Secundino López Puente Marta López‐Alonso Søren Saxmose Nielsen Alena Pechová Mariana Petkova Sebastien Girault Alessandro Broglia Beatriz Guerra Matteo Lorenzo Innocenti Ernesto Liébana Gloria López‐Gálvez Paola Manini Pietro Stella Luisa Peixe Maximum levels of cross‐contamination for 24 antimicrobial active substances in non‐target feed. Part 11: Sulfonamides
description	Abstract The specific concentrations of sulfonamides in non‐target feed for food‐producing animals, below which there would not be an effect on the emergence of, and/or selection for, resistance in bacteria relevant for human and animal health, as well as the specific antimicrobial concentrations in feed which have an effect in terms of growth promotion/increased yield were assessed by EFSA in collaboration with EMA. Details of the methodology used for this assessment, associated data gaps and uncertainties, are presented in a separate document. To address antimicrobial resistance, the Feed Antimicrobial Resistance Selection Concentration (FARSC) model developed specifically for the assessment was applied. However, due to the lack of data on the parameters required to calculate the FARSC, it was not possible to conclude the assessment until further experimental data are available. To address growth promotion, data from scientific publications obtained from an extensive literature review were used. Levels in feed that showed to have an effect on growth promotion/increased yield were identified for three sulfonamides: sulfamethazine, sulfathiazole and sulfamerazine. It was recommended to carry out studies to generate the data that are required to fill the gaps which prevented the calculation of the FARSC for these antimicrobials.
format	article
author	EFSA Panel on Biological Hazards (BIOHAZ) Konstantinos Koutsoumanis Ana Allende Avelino Alvarez‐Ordóñez Declan Bolton Sara Bover‐Cid Marianne Chemaly Robert Davies Alessandra De Cesare Lieve Herman Friederike Hilbert Roland Lindqvist Maarten Nauta Giuseppe Ru Marion Simmons Panagiotis Skandamis Elisabetta Suffredini Dan I. Andersson Vasileios Bampidis Johan Bengtsson‐Palme Damien Bouchard Aude Ferran Maryline Kouba Secundino López Puente Marta López‐Alonso Søren Saxmose Nielsen Alena Pechová Mariana Petkova Sebastien Girault Alessandro Broglia Beatriz Guerra Matteo Lorenzo Innocenti Ernesto Liébana Gloria López‐Gálvez Paola Manini Pietro Stella Luisa Peixe
author_facet	EFSA Panel on Biological Hazards (BIOHAZ) Konstantinos Koutsoumanis Ana Allende Avelino Alvarez‐Ordóñez Declan Bolton Sara Bover‐Cid Marianne Chemaly Robert Davies Alessandra De Cesare Lieve Herman Friederike Hilbert Roland Lindqvist Maarten Nauta Giuseppe Ru Marion Simmons Panagiotis Skandamis Elisabetta Suffredini Dan I. Andersson Vasileios Bampidis Johan Bengtsson‐Palme Damien Bouchard Aude Ferran Maryline Kouba Secundino López Puente Marta López‐Alonso Søren Saxmose Nielsen Alena Pechová Mariana Petkova Sebastien Girault Alessandro Broglia Beatriz Guerra Matteo Lorenzo Innocenti Ernesto Liébana Gloria López‐Gálvez Paola Manini Pietro Stella Luisa Peixe
author_sort	EFSA Panel on Biological Hazards (BIOHAZ)
title	Maximum levels of cross‐contamination for 24 antimicrobial active substances in non‐target feed. Part 11: Sulfonamides
title_short	Maximum levels of cross‐contamination for 24 antimicrobial active substances in non‐target feed. Part 11: Sulfonamides
title_full	Maximum levels of cross‐contamination for 24 antimicrobial active substances in non‐target feed. Part 11: Sulfonamides
title_fullStr	Maximum levels of cross‐contamination for 24 antimicrobial active substances in non‐target feed. Part 11: Sulfonamides
title_full_unstemmed	Maximum levels of cross‐contamination for 24 antimicrobial active substances in non‐target feed. Part 11: Sulfonamides
title_sort	maximum levels of cross‐contamination for 24 antimicrobial active substances in non‐target feed. part 11: sulfonamides
publisher	Wiley
publishDate	2021
url	https://doaj.org/article/375e5cf464314db79f4d372ed6c4e1eb
work_keys_str_mv	AT efsapanelonbiologicalhazardsbiohaz maximumlevelsofcrosscontaminationfor24antimicrobialactivesubstancesinnontargetfeedpart11sulfonamides AT konstantinoskoutsoumanis maximumlevelsofcrosscontaminationfor24antimicrobialactivesubstancesinnontargetfeedpart11sulfonamides AT anaallende maximumlevelsofcrosscontaminationfor24antimicrobialactivesubstancesinnontargetfeedpart11sulfonamides AT avelinoalvarezordonez maximumlevelsofcrosscontaminationfor24antimicrobialactivesubstancesinnontargetfeedpart11sulfonamides AT declanbolton maximumlevelsofcrosscontaminationfor24antimicrobialactivesubstancesinnontargetfeedpart11sulfonamides AT sarabovercid maximumlevelsofcrosscontaminationfor24antimicrobialactivesubstancesinnontargetfeedpart11sulfonamides AT mariannechemaly maximumlevelsofcrosscontaminationfor24antimicrobialactivesubstancesinnontargetfeedpart11sulfonamides AT robertdavies maximumlevelsofcrosscontaminationfor24antimicrobialactivesubstancesinnontargetfeedpart11sulfonamides AT alessandradecesare maximumlevelsofcrosscontaminationfor24antimicrobialactivesubstancesinnontargetfeedpart11sulfonamides AT lieveherman maximumlevelsofcrosscontaminationfor24antimicrobialactivesubstancesinnontargetfeedpart11sulfonamides AT friederikehilbert maximumlevelsofcrosscontaminationfor24antimicrobialactivesubstancesinnontargetfeedpart11sulfonamides AT rolandlindqvist maximumlevelsofcrosscontaminationfor24antimicrobialactivesubstancesinnontargetfeedpart11sulfonamides AT maartennauta maximumlevelsofcrosscontaminationfor24antimicrobialactivesubstancesinnontargetfeedpart11sulfonamides AT giusepperu maximumlevelsofcrosscontaminationfor24antimicrobialactivesubstancesinnontargetfeedpart11sulfonamides AT marionsimmons maximumlevelsofcrosscontaminationfor24antimicrobialactivesubstancesinnontargetfeedpart11sulfonamides AT panagiotisskandamis maximumlevelsofcrosscontaminationfor24antimicrobialactivesubstancesinnontargetfeedpart11sulfonamides AT elisabettasuffredini maximumlevelsofcrosscontaminationfor24antimicrobialactivesubstancesinnontargetfeedpart11sulfonamides AT daniandersson maximumlevelsofcrosscontaminationfor24antimicrobialactivesubstancesinnontargetfeedpart11sulfonamides AT vasileiosbampidis maximumlevelsofcrosscontaminationfor24antimicrobialactivesubstancesinnontargetfeedpart11sulfonamides AT johanbengtssonpalme maximumlevelsofcrosscontaminationfor24antimicrobialactivesubstancesinnontargetfeedpart11sulfonamides AT damienbouchard maximumlevelsofcrosscontaminationfor24antimicrobialactivesubstancesinnontargetfeedpart11sulfonamides AT audeferran maximumlevelsofcrosscontaminationfor24antimicrobialactivesubstancesinnontargetfeedpart11sulfonamides AT marylinekouba maximumlevelsofcrosscontaminationfor24antimicrobialactivesubstancesinnontargetfeedpart11sulfonamides AT secundinolopezpuente maximumlevelsofcrosscontaminationfor24antimicrobialactivesubstancesinnontargetfeedpart11sulfonamides AT martalopezalonso maximumlevelsofcrosscontaminationfor24antimicrobialactivesubstancesinnontargetfeedpart11sulfonamides AT sørensaxmosenielsen maximumlevelsofcrosscontaminationfor24antimicrobialactivesubstancesinnontargetfeedpart11sulfonamides AT alenapechova maximumlevelsofcrosscontaminationfor24antimicrobialactivesubstancesinnontargetfeedpart11sulfonamides AT marianapetkova maximumlevelsofcrosscontaminationfor24antimicrobialactivesubstancesinnontargetfeedpart11sulfonamides AT sebastiengirault maximumlevelsofcrosscontaminationfor24antimicrobialactivesubstancesinnontargetfeedpart11sulfonamides AT alessandrobroglia maximumlevelsofcrosscontaminationfor24antimicrobialactivesubstancesinnontargetfeedpart11sulfonamides AT beatrizguerra maximumlevelsofcrosscontaminationfor24antimicrobialactivesubstancesinnontargetfeedpart11sulfonamides AT matteolorenzoinnocenti maximumlevelsofcrosscontaminationfor24antimicrobialactivesubstancesinnontargetfeedpart11sulfonamides AT ernestoliebana maximumlevelsofcrosscontaminationfor24antimicrobialactivesubstancesinnontargetfeedpart11sulfonamides AT glorialopezgalvez maximumlevelsofcrosscontaminationfor24antimicrobialactivesubstancesinnontargetfeedpart11sulfonamides AT paolamanini maximumlevelsofcrosscontaminationfor24antimicrobialactivesubstancesinnontargetfeedpart11sulfonamides AT pietrostella maximumlevelsofcrosscontaminationfor24antimicrobialactivesubstancesinnontargetfeedpart11sulfonamides AT luisapeixe maximumlevelsofcrosscontaminationfor24antimicrobialactivesubstancesinnontargetfeedpart11sulfonamides
_version_	1718416818691899392

Maximum levels of cross‐contamination for 24 antimicrobial active substances in non‐target feed. Part 11: Sulfonamides

Ejemplares similares