Uncovering pseudotemporal trajectories with covariates from single cell and bulk expression data

Cross-sectional omic data often have non-homogeneous genetic, phenotypic, or environmental backgrounds. Here, the authors develop a statistical framework to infer pseudotime trajectories in the presence of such factors as well as their interactions in both single-cell and bulk gene expression analys...

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Autores principales: Kieran R Campbell, Christopher Yau
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2018
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Acceso en línea:https://doaj.org/article/3761c004c4af44ac8a270dfce339a057
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