Artificial accommodating intraocular lens powered by an ion polymer-metal composite actuator.

The current method of controlling the focus of an accommodating intraocular lens is based on ciliary muscle contraction and cannot be used in older patients with presbyopia. We aimed to develop a dynamically accommodating intraocular lens powered by a membrane-shaped ion polymer metal composite actu...

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Autores principales:	Tetsuya Horiuchi, Toshifumi Mihashi, Sujin Hoshi, Fumiki Okamoto, Tetsuro Oshika
Formato:	article
Lenguaje:	EN
Publicado:	Public Library of Science (PLoS) 2021
Materias:	Medicine R Science Q
Acceso en línea:	https://doaj.org/article/3769af8bdd4441e083c78c0e40ef76b7
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id	oai:doaj.org-article:3769af8bdd4441e083c78c0e40ef76b7
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spelling	oai:doaj.org-article:3769af8bdd4441e083c78c0e40ef76b72021-12-02T20:10:14ZArtificial accommodating intraocular lens powered by an ion polymer-metal composite actuator.1932-620310.1371/journal.pone.0252986https://doaj.org/article/3769af8bdd4441e083c78c0e40ef76b72021-01-01T00:00:00Zhttps://doi.org/10.1371/journal.pone.0252986https://doaj.org/toc/1932-6203The current method of controlling the focus of an accommodating intraocular lens is based on ciliary muscle contraction and cannot be used in older patients with presbyopia. We aimed to develop a dynamically accommodating intraocular lens powered by a membrane-shaped ion polymer metal composite actuator that is thin enough to be inserted in the eye. This study addresses two key problems identified in our previous accommodating intraocular lens prototype: the lack of repeatability due to the use of swine lenses instead of artificial lenses and the occurrence of a sixth order aberration. Thus, we present a new accommodating intraocular lens design and a method to transfer energy to actuators. To accommodate lens deformation and depth of focus, we used a membrane-shaped ion polymer metal composite actuator, thin enough to be inserted in the eye, and used an artificial silicone lens. To prevent the sixth order aberration, we included a ring between the ion polymer metal composite actuator and the lens. Different voltage patterns were applied to the IPMC actuator and changes in focus were observed. We were able to obtain repeatability and prevent the sixth order aberration. The dioptric power changed to ±0.23 D when ±1.5 V was used; however, at >1.5 V, a large accommodating range occurred, in addition to astigmatic vision. Thus, we have developed a novel prototype that is completely artificial, allowing reproducible and repeatable results. Visual accommodative demands were successfully met; however, although astigmatic vision was lessened, it was not completely eradicated.Tetsuya HoriuchiToshifumi MihashiSujin HoshiFumiki OkamotoTetsuro OshikaPublic Library of Science (PLoS)articleMedicineRScienceQENPLoS ONE, Vol 16, Iss 6, p e0252986 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Medicine R Science Q
spellingShingle	Medicine R Science Q Tetsuya Horiuchi Toshifumi Mihashi Sujin Hoshi Fumiki Okamoto Tetsuro Oshika Artificial accommodating intraocular lens powered by an ion polymer-metal composite actuator.
description	The current method of controlling the focus of an accommodating intraocular lens is based on ciliary muscle contraction and cannot be used in older patients with presbyopia. We aimed to develop a dynamically accommodating intraocular lens powered by a membrane-shaped ion polymer metal composite actuator that is thin enough to be inserted in the eye. This study addresses two key problems identified in our previous accommodating intraocular lens prototype: the lack of repeatability due to the use of swine lenses instead of artificial lenses and the occurrence of a sixth order aberration. Thus, we present a new accommodating intraocular lens design and a method to transfer energy to actuators. To accommodate lens deformation and depth of focus, we used a membrane-shaped ion polymer metal composite actuator, thin enough to be inserted in the eye, and used an artificial silicone lens. To prevent the sixth order aberration, we included a ring between the ion polymer metal composite actuator and the lens. Different voltage patterns were applied to the IPMC actuator and changes in focus were observed. We were able to obtain repeatability and prevent the sixth order aberration. The dioptric power changed to ±0.23 D when ±1.5 V was used; however, at >1.5 V, a large accommodating range occurred, in addition to astigmatic vision. Thus, we have developed a novel prototype that is completely artificial, allowing reproducible and repeatable results. Visual accommodative demands were successfully met; however, although astigmatic vision was lessened, it was not completely eradicated.
format	article
author	Tetsuya Horiuchi Toshifumi Mihashi Sujin Hoshi Fumiki Okamoto Tetsuro Oshika
author_facet	Tetsuya Horiuchi Toshifumi Mihashi Sujin Hoshi Fumiki Okamoto Tetsuro Oshika
author_sort	Tetsuya Horiuchi
title	Artificial accommodating intraocular lens powered by an ion polymer-metal composite actuator.
title_short	Artificial accommodating intraocular lens powered by an ion polymer-metal composite actuator.
title_full	Artificial accommodating intraocular lens powered by an ion polymer-metal composite actuator.
title_fullStr	Artificial accommodating intraocular lens powered by an ion polymer-metal composite actuator.
title_full_unstemmed	Artificial accommodating intraocular lens powered by an ion polymer-metal composite actuator.
title_sort	artificial accommodating intraocular lens powered by an ion polymer-metal composite actuator.
publisher	Public Library of Science (PLoS)
publishDate	2021
url	https://doaj.org/article/3769af8bdd4441e083c78c0e40ef76b7
work_keys_str_mv	AT tetsuyahoriuchi artificialaccommodatingintraocularlenspoweredbyanionpolymermetalcompositeactuator AT toshifumimihashi artificialaccommodatingintraocularlenspoweredbyanionpolymermetalcompositeactuator AT sujinhoshi artificialaccommodatingintraocularlenspoweredbyanionpolymermetalcompositeactuator AT fumikiokamoto artificialaccommodatingintraocularlenspoweredbyanionpolymermetalcompositeactuator AT tetsurooshika artificialaccommodatingintraocularlenspoweredbyanionpolymermetalcompositeactuator
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Artificial accommodating intraocular lens powered by an ion polymer-metal composite actuator.

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