Structural analysis of human ARS2 as a platform for co-transcriptional RNA sorting

Arsenic resistance protein 2 (ARS2) plays an important role in nuclear RNA metabolism and interacts with the nuclear cap-binding complex (CBC). Here the authors present the human ARS2 structure and identify regions important for its interactions with binding partners supporting that mutually exclusi...

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Autores principales: Wiebke Manuela Schulze, Frank Stein, Mandy Rettel, Max Nanao, Stephen Cusack
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2018
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Acceso en línea:https://doaj.org/article/37723f35668a4c859bee5cfff4a955b9
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