The Small t Antigen of JC Virus Antagonizes RIG-I-Mediated Innate Immunity by Inhibiting TRIM25’s RNA Binding Ability

The innate immune response is the first line of defense against viral pathogens, and in turn, many viruses have evolved strategies to evade detection by the host’s innate immune surveillance machinery. Investigation of the interplay between viruses and the innate immune response provides valuable i...

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Autores principales:	Cindy Chiang, Steve Dvorkin, Jessica J. Chiang, Rachel B. Potter, Michaela U. Gack
Formato:	article
Lenguaje:	EN
Publicado:	American Society for Microbiology 2021
Materias:	Microbiology QR1-502
Acceso en línea:	https://doaj.org/article/37785a448acb47b2bd96cf8d1910a735
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spelling	oai:doaj.org-article:37785a448acb47b2bd96cf8d1910a7352021-11-03T18:56:09ZThe Small t Antigen of JC Virus Antagonizes RIG-I-Mediated Innate Immunity by Inhibiting TRIM25’s RNA Binding Ability2150-751110.1128/mBio.00620-21https://doaj.org/article/37785a448acb47b2bd96cf8d1910a7352021-04-01T00:00:00Zhttps://journals.asm.org/doi/10.1128/mBio.00620-21https://doaj.org/toc/2150-7511 The innate immune response is the first line of defense against viral pathogens, and in turn, many viruses have evolved strategies to evade detection by the host’s innate immune surveillance machinery. Investigation of the interplay between viruses and the innate immune response provides valuable insight into potential therapeutic targets against viral infectious diseases.Cindy ChiangSteve DvorkinJessica J. ChiangRachel B. PotterMichaela U. GackAmerican Society for MicrobiologyarticleMicrobiologyQR1-502ENmBio, Vol 12, Iss 2 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Microbiology QR1-502
spellingShingle	Microbiology QR1-502 Cindy Chiang Steve Dvorkin Jessica J. Chiang Rachel B. Potter Michaela U. Gack The Small t Antigen of JC Virus Antagonizes RIG-I-Mediated Innate Immunity by Inhibiting TRIM25’s RNA Binding Ability
description	The innate immune response is the first line of defense against viral pathogens, and in turn, many viruses have evolved strategies to evade detection by the host’s innate immune surveillance machinery. Investigation of the interplay between viruses and the innate immune response provides valuable insight into potential therapeutic targets against viral infectious diseases.
format	article
author	Cindy Chiang Steve Dvorkin Jessica J. Chiang Rachel B. Potter Michaela U. Gack
author_facet	Cindy Chiang Steve Dvorkin Jessica J. Chiang Rachel B. Potter Michaela U. Gack
author_sort	Cindy Chiang
title	The Small t Antigen of JC Virus Antagonizes RIG-I-Mediated Innate Immunity by Inhibiting TRIM25’s RNA Binding Ability
title_short	The Small t Antigen of JC Virus Antagonizes RIG-I-Mediated Innate Immunity by Inhibiting TRIM25’s RNA Binding Ability
title_full	The Small t Antigen of JC Virus Antagonizes RIG-I-Mediated Innate Immunity by Inhibiting TRIM25’s RNA Binding Ability
title_fullStr	The Small t Antigen of JC Virus Antagonizes RIG-I-Mediated Innate Immunity by Inhibiting TRIM25’s RNA Binding Ability
title_full_unstemmed	The Small t Antigen of JC Virus Antagonizes RIG-I-Mediated Innate Immunity by Inhibiting TRIM25’s RNA Binding Ability
title_sort	small t antigen of jc virus antagonizes rig-i-mediated innate immunity by inhibiting trim25’s rna binding ability
publisher	American Society for Microbiology
publishDate	2021
url	https://doaj.org/article/37785a448acb47b2bd96cf8d1910a735
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The Small t Antigen of JC Virus Antagonizes RIG-I-Mediated Innate Immunity by Inhibiting TRIM25’s RNA Binding Ability

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