Interaction between HLA-DRB1-DQB1 haplotypes in Sardinian multiple sclerosis population.

Interaction between HLA-DRB1-DQB1 haplotypes in Sardinian multiple sclerosis population.

We performed a case-control study in 2,555 multiple sclerosis (MS) Sardinian patients and 1,365 healthy ethnically matched controls, analyzing the interactions between HLA-DRB1-DQB1 haplotypes and defining a rank of genotypes conferring a variable degree of risk to the disease. Four haplotypes were...

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Autores principales: Eleonora Cocco, Raffaele Murru, Gianna Costa, Amit Kumar, Enrico Pieroni, Cristina Melis, Luigi Barberini, Claudia Sardu, Lorena Lorefice, Giuseppe Fenu, Jessica Frau, Giancarlo Coghe, Nicola Carboni, Maria Giovanna Marrosu
Formato: article
Lenguaje:EN
Publicado: Public Library of Science (PLoS) 2013
Materias:
Medicine
R
Science
Q
Acceso en línea:https://doaj.org/article/377ae2525b204c589623a27a46f8f3a8
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