Cardiac MRI structural and functional predictors of left ventricular ejection fraction recovery following PVC catheter ablation

Cardiac MRI structural and functional predictors of left ventricular ejection fraction recovery following PVC catheter ablation

Abstract Frequent premature ventricular contractions (PVCs) can induce cardiomyopathy (PVC CM). We sought to use cardiac magnetic resonance imaging (CMR) to quantify changes in cardiac structure and function of cardiomyopathy patients following catheter ablation for PVCs. Patients undergoing PVC abl...

Descripción completa

Guardado en:
Detalles Bibliográficos
Autores principales: Jessica Mao, Eric Xie, Ela Chamera, Joao A. C. Lima, Jonathan Chrispin
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2021
Materias:
Medicine
R
Science
Q
Acceso en línea:https://doaj.org/article/3790e0fdd895468cb39bd7249865103c
Etiquetas: Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!
id oai:doaj.org-article:3790e0fdd895468cb39bd7249865103c
record_format dspace
spelling oai:doaj.org-article:3790e0fdd895468cb39bd7249865103c2021-12-02T15:51:11ZCardiac MRI structural and functional predictors of left ventricular ejection fraction recovery following PVC catheter ablation10.1038/s41598-021-87754-22045-2322https://doaj.org/article/3790e0fdd895468cb39bd7249865103c2021-04-01T00:00:00Zhttps://doi.org/10.1038/s41598-021-87754-2https://doaj.org/toc/2045-2322Abstract Frequent premature ventricular contractions (PVCs) can induce cardiomyopathy (PVC CM). We sought to use cardiac magnetic resonance imaging (CMR) to quantify changes in cardiac structure and function of cardiomyopathy patients following catheter ablation for PVCs. Patients undergoing PVC ablation at the Johns Hopkins Hospital with pre-procedural CMR from 2010 to 2018 were included in this study. CMR Images were analyzed to collect information on cardiac structure and function as well as to quantify scar. Of the total 51 included patients, PVC CM (LVEF < 45%) was observed in 51% (n = 29). Of these, 19 had post-ablation ejection fractions quantified, with 78.9% (n = 15) recovering function. Global longitudinal strain was significantly correlated with LVEF (OR 1.831, p < 0.01) but did not predict recovery of function. RV origin of PVCs was more common in the preserved LVEF group but was also significantly correlated with persistently reduced EF post-ablation in the PVC CM group. Scar burden was not correlated with either cardiac function or post-ablation recovery of function. In this cohort, there were no significant CMR findings to predict subsequent recovery of EF after ablation among those with PVC CM. PVC origin in the RV was associated with persistently reduced LVEF after ablation.Jessica MaoEric XieEla ChameraJoao A. C. LimaJonathan ChrispinNature PortfolioarticleMedicineRScienceQENScientific Reports, Vol 11, Iss 1, Pp 1-8 (2021)
institution DOAJ
collection DOAJ
language EN
topic Medicine
R
Science
Q
spellingShingle Medicine
R
Science
Q
Jessica Mao
Eric Xie
Ela Chamera
Joao A. C. Lima
Jonathan Chrispin
Cardiac MRI structural and functional predictors of left ventricular ejection fraction recovery following PVC catheter ablation
description Abstract Frequent premature ventricular contractions (PVCs) can induce cardiomyopathy (PVC CM). We sought to use cardiac magnetic resonance imaging (CMR) to quantify changes in cardiac structure and function of cardiomyopathy patients following catheter ablation for PVCs. Patients undergoing PVC ablation at the Johns Hopkins Hospital with pre-procedural CMR from 2010 to 2018 were included in this study. CMR Images were analyzed to collect information on cardiac structure and function as well as to quantify scar. Of the total 51 included patients, PVC CM (LVEF < 45%) was observed in 51% (n = 29). Of these, 19 had post-ablation ejection fractions quantified, with 78.9% (n = 15) recovering function. Global longitudinal strain was significantly correlated with LVEF (OR 1.831, p < 0.01) but did not predict recovery of function. RV origin of PVCs was more common in the preserved LVEF group but was also significantly correlated with persistently reduced EF post-ablation in the PVC CM group. Scar burden was not correlated with either cardiac function or post-ablation recovery of function. In this cohort, there were no significant CMR findings to predict subsequent recovery of EF after ablation among those with PVC CM. PVC origin in the RV was associated with persistently reduced LVEF after ablation.
format article
author Jessica Mao
Eric Xie
Ela Chamera
Joao A. C. Lima
Jonathan Chrispin
author_facet Jessica Mao
Eric Xie
Ela Chamera
Joao A. C. Lima
Jonathan Chrispin
author_sort Jessica Mao
title Cardiac MRI structural and functional predictors of left ventricular ejection fraction recovery following PVC catheter ablation
title_short Cardiac MRI structural and functional predictors of left ventricular ejection fraction recovery following PVC catheter ablation
title_full Cardiac MRI structural and functional predictors of left ventricular ejection fraction recovery following PVC catheter ablation
title_fullStr Cardiac MRI structural and functional predictors of left ventricular ejection fraction recovery following PVC catheter ablation
title_full_unstemmed Cardiac MRI structural and functional predictors of left ventricular ejection fraction recovery following PVC catheter ablation
title_sort cardiac mri structural and functional predictors of left ventricular ejection fraction recovery following pvc catheter ablation
publisher Nature Portfolio
publishDate 2021
url https://doaj.org/article/3790e0fdd895468cb39bd7249865103c
work_keys_str_mv AT jessicamao cardiacmristructuralandfunctionalpredictorsofleftventricularejectionfractionrecoveryfollowingpvccatheterablation
AT ericxie cardiacmristructuralandfunctionalpredictorsofleftventricularejectionfractionrecoveryfollowingpvccatheterablation
AT elachamera cardiacmristructuralandfunctionalpredictorsofleftventricularejectionfractionrecoveryfollowingpvccatheterablation
AT joaoaclima cardiacmristructuralandfunctionalpredictorsofleftventricularejectionfractionrecoveryfollowingpvccatheterablation
AT jonathanchrispin cardiacmristructuralandfunctionalpredictorsofleftventricularejectionfractionrecoveryfollowingpvccatheterablation
_version_ 1718385626135396352

Ejemplares similares