Targeting murine leukemic stem cells by antibody functionalized mesoporous silica nanoparticles

Targeting murine leukemic stem cells by antibody functionalized mesoporous silica nanoparticles

Abstract Acute leukemia is initiated and maintained by leukemia stem cells (LSCs) and therefore there is great interest to develop innovative therapeutic approaches which target LSCs. Here we show that mesoporous silica nanoparticles (MSNs) functionalized with succinic anhydride, tagged with an anti...

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Autores principales: Tamoghna Mandal, Michaela Beck, Nicole Kirsten, Mika Lindén, Christian Buske
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2018
Materias:
Medicine
R
Science
Q
Acceso en línea:https://doaj.org/article/3797cf968779482ab6d8630918678c02
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