Detecting and phasing minor single-nucleotide variants from long-read sequencing data
Cellular genetic heterogeneity is common across biological conditions, yet application of long-read sequencing to this subject is limited by error rates. Here, the authors present iGDA, a tool for detection and phasing of minor variants from long-read sequencing data, allowing accurate reconstructio...
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Main Authors: | Zhixing Feng, Jose C. Clemente, Brandon Wong, Eric E. Schadt |
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Format: | article |
Language: | EN |
Published: |
Nature Portfolio
2021
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Subjects: | |
Online Access: | https://doaj.org/article/37aa516a22e74b34bed4e369ee1e4b98 |
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