Resveratrol, by modulating RNA processing factor levels, can influence the alternative splicing of pre-mRNAs.
Alternative pre-mRNA splicing defects can contribute to, or result from, various diseases, including cancer. Aberrant mRNAs, splicing factors and other RNA processing factors have therefore become targets for new therapeutic interventions. Here we report that the natural polyphenol resveratrol can m...
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Autores principales: | M Andrea Markus, Francine Z Marques, Brian J Morris |
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Formato: | article |
Lenguaje: | EN |
Publicado: |
Public Library of Science (PLoS)
2011
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Materias: | |
Acceso en línea: | https://doaj.org/article/37ad2a27095b42f98805d70810543c20 |
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