Resveratrol, by modulating RNA processing factor levels, can influence the alternative splicing of pre-mRNAs.
Alternative pre-mRNA splicing defects can contribute to, or result from, various diseases, including cancer. Aberrant mRNAs, splicing factors and other RNA processing factors have therefore become targets for new therapeutic interventions. Here we report that the natural polyphenol resveratrol can m...
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Auteurs principaux: | M Andrea Markus, Francine Z Marques, Brian J Morris |
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Format: | article |
Langue: | EN |
Publié: |
Public Library of Science (PLoS)
2011
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Accès en ligne: | https://doaj.org/article/37ad2a27095b42f98805d70810543c20 |
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