Structural library and visualization of endogenously oxidized phosphatidylcholines using mass spectrometry-based techniques

Structural library and visualization of endogenously oxidized phosphatidylcholines using mass spectrometry-based techniques

Oxidized phosphatidylcholines (oxPCs) are a structurally diverse class of lipids associated with various diseases. Here, the authors use mass spectrometry to construct a spectral library of 465 oxPCs and subsequently profile oxPCs formed during acetaminophen-induced acute liver failure in mice.

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Autores principales: Yuta Matsuoka, Masatomo Takahashi, Yuki Sugiura, Yoshihiro Izumi, Kazuhiro Nishiyama, Motohiro Nishida, Makoto Suematsu, Takeshi Bamba, Ken-ichi Yamada
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2021
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Science
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Acceso en línea:https://doaj.org/article/37bab6945355410fb3f591261ec7e897
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