Evolving Diagnostic Criteria for Arrhythmogenic Cardiomyopathy

Abstract Criteria for diagnosis of arrhythmogenic cardiomyopathy (ACM) were first proposed in 1994 and revised in 2010 by a Task Force. Although the Task Force criteria demonstrated a good accuracy for diagnosis of the original right ventricular phenotype (arrhythmogenic right ventricular cardiomyop...

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Autores principales: Domenico Corrado, Alessandro Zorzi, Alberto Cipriani, Barbara Bauce, Riccardo Bariani, Giorgia Beffagna, Manuel De Lazzari, Federico Migliore, Kalliopi Pilichou, Alessandra Rampazzo, Ilaria Rigato, Stefania Rizzo, Gaetano Thiene, Martina Perazzolo Marra, Cristina Basso
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Publicado: Wiley 2021
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spelling oai:doaj.org-article:37bbe4398dd24249a34002d7ee2e8e2f2021-11-23T11:36:34ZEvolving Diagnostic Criteria for Arrhythmogenic Cardiomyopathy10.1161/JAHA.121.0219872047-9980https://doaj.org/article/37bbe4398dd24249a34002d7ee2e8e2f2021-09-01T00:00:00Zhttps://www.ahajournals.org/doi/10.1161/JAHA.121.021987https://doaj.org/toc/2047-9980Abstract Criteria for diagnosis of arrhythmogenic cardiomyopathy (ACM) were first proposed in 1994 and revised in 2010 by a Task Force. Although the Task Force criteria demonstrated a good accuracy for diagnosis of the original right ventricular phenotype (arrhythmogenic right ventricular cardiomyopathy), they lacked sensitivity for identification of the expanding phenotypic spectrum of ACM, which includes left‐sided variants and did not incorporate late‐gadolinium enhancement findings by cardiac magnetic resonance. The 2020 International criteria (“Padua criteria”) have been developed by International experts with the aim to improve the diagnosis of ACM by providing new criteria for the diagnosis of left ventricular phenotypic features. The key upgrade was the incorporation of tissue characterization findings by cardiac magnetic resonance for noninvasive detection of late‐gadolinium enhancement/myocardial fibrosis that are determinants for characterization of arrhythmogenic biventricular and left ventricular cardiomyopathy. The 2020 International criteria are heavily dependent on cardiac magnetic resonance, which has become mandatory to characterize the ACM phenotype and to exclude other diagnoses. New criteria regarding left ventricular depolarization and repolarization ECG abnormalities and ventricular arrhythmias of left ventricular origin were also provided. This article reviews the evolving approach to diagnosis of ACM, going back to the 1994 and 2010 International Task Force criteria and then grapple with the modern 2020 International criteria.Domenico CorradoAlessandro ZorziAlberto CiprianiBarbara BauceRiccardo BarianiGiorgia BeffagnaManuel De LazzariFederico MiglioreKalliopi PilichouAlessandra RampazzoIlaria RigatoStefania RizzoGaetano ThieneMartina Perazzolo MarraCristina BassoWileyarticlecardiac magnetic resonancecardiomyopathydiagnosissudden deathventricular arrhythmiaDiseases of the circulatory (Cardiovascular) systemRC666-701ENJournal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 10, Iss 18 (2021)
institution DOAJ
collection DOAJ
language EN
topic cardiac magnetic resonance
cardiomyopathy
diagnosis
sudden death
ventricular arrhythmia
Diseases of the circulatory (Cardiovascular) system
RC666-701
spellingShingle cardiac magnetic resonance
cardiomyopathy
diagnosis
sudden death
ventricular arrhythmia
Diseases of the circulatory (Cardiovascular) system
RC666-701
Domenico Corrado
Alessandro Zorzi
Alberto Cipriani
Barbara Bauce
Riccardo Bariani
Giorgia Beffagna
Manuel De Lazzari
Federico Migliore
Kalliopi Pilichou
Alessandra Rampazzo
Ilaria Rigato
Stefania Rizzo
Gaetano Thiene
Martina Perazzolo Marra
Cristina Basso
Evolving Diagnostic Criteria for Arrhythmogenic Cardiomyopathy
description Abstract Criteria for diagnosis of arrhythmogenic cardiomyopathy (ACM) were first proposed in 1994 and revised in 2010 by a Task Force. Although the Task Force criteria demonstrated a good accuracy for diagnosis of the original right ventricular phenotype (arrhythmogenic right ventricular cardiomyopathy), they lacked sensitivity for identification of the expanding phenotypic spectrum of ACM, which includes left‐sided variants and did not incorporate late‐gadolinium enhancement findings by cardiac magnetic resonance. The 2020 International criteria (“Padua criteria”) have been developed by International experts with the aim to improve the diagnosis of ACM by providing new criteria for the diagnosis of left ventricular phenotypic features. The key upgrade was the incorporation of tissue characterization findings by cardiac magnetic resonance for noninvasive detection of late‐gadolinium enhancement/myocardial fibrosis that are determinants for characterization of arrhythmogenic biventricular and left ventricular cardiomyopathy. The 2020 International criteria are heavily dependent on cardiac magnetic resonance, which has become mandatory to characterize the ACM phenotype and to exclude other diagnoses. New criteria regarding left ventricular depolarization and repolarization ECG abnormalities and ventricular arrhythmias of left ventricular origin were also provided. This article reviews the evolving approach to diagnosis of ACM, going back to the 1994 and 2010 International Task Force criteria and then grapple with the modern 2020 International criteria.
format article
author Domenico Corrado
Alessandro Zorzi
Alberto Cipriani
Barbara Bauce
Riccardo Bariani
Giorgia Beffagna
Manuel De Lazzari
Federico Migliore
Kalliopi Pilichou
Alessandra Rampazzo
Ilaria Rigato
Stefania Rizzo
Gaetano Thiene
Martina Perazzolo Marra
Cristina Basso
author_facet Domenico Corrado
Alessandro Zorzi
Alberto Cipriani
Barbara Bauce
Riccardo Bariani
Giorgia Beffagna
Manuel De Lazzari
Federico Migliore
Kalliopi Pilichou
Alessandra Rampazzo
Ilaria Rigato
Stefania Rizzo
Gaetano Thiene
Martina Perazzolo Marra
Cristina Basso
author_sort Domenico Corrado
title Evolving Diagnostic Criteria for Arrhythmogenic Cardiomyopathy
title_short Evolving Diagnostic Criteria for Arrhythmogenic Cardiomyopathy
title_full Evolving Diagnostic Criteria for Arrhythmogenic Cardiomyopathy
title_fullStr Evolving Diagnostic Criteria for Arrhythmogenic Cardiomyopathy
title_full_unstemmed Evolving Diagnostic Criteria for Arrhythmogenic Cardiomyopathy
title_sort evolving diagnostic criteria for arrhythmogenic cardiomyopathy
publisher Wiley
publishDate 2021
url https://doaj.org/article/37bbe4398dd24249a34002d7ee2e8e2f
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