Evolving Diagnostic Criteria for Arrhythmogenic Cardiomyopathy
Abstract Criteria for diagnosis of arrhythmogenic cardiomyopathy (ACM) were first proposed in 1994 and revised in 2010 by a Task Force. Although the Task Force criteria demonstrated a good accuracy for diagnosis of the original right ventricular phenotype (arrhythmogenic right ventricular cardiomyop...
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Wiley
2021
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oai:doaj.org-article:37bbe4398dd24249a34002d7ee2e8e2f2021-11-23T11:36:34ZEvolving Diagnostic Criteria for Arrhythmogenic Cardiomyopathy10.1161/JAHA.121.0219872047-9980https://doaj.org/article/37bbe4398dd24249a34002d7ee2e8e2f2021-09-01T00:00:00Zhttps://www.ahajournals.org/doi/10.1161/JAHA.121.021987https://doaj.org/toc/2047-9980Abstract Criteria for diagnosis of arrhythmogenic cardiomyopathy (ACM) were first proposed in 1994 and revised in 2010 by a Task Force. Although the Task Force criteria demonstrated a good accuracy for diagnosis of the original right ventricular phenotype (arrhythmogenic right ventricular cardiomyopathy), they lacked sensitivity for identification of the expanding phenotypic spectrum of ACM, which includes left‐sided variants and did not incorporate late‐gadolinium enhancement findings by cardiac magnetic resonance. The 2020 International criteria (“Padua criteria”) have been developed by International experts with the aim to improve the diagnosis of ACM by providing new criteria for the diagnosis of left ventricular phenotypic features. The key upgrade was the incorporation of tissue characterization findings by cardiac magnetic resonance for noninvasive detection of late‐gadolinium enhancement/myocardial fibrosis that are determinants for characterization of arrhythmogenic biventricular and left ventricular cardiomyopathy. The 2020 International criteria are heavily dependent on cardiac magnetic resonance, which has become mandatory to characterize the ACM phenotype and to exclude other diagnoses. New criteria regarding left ventricular depolarization and repolarization ECG abnormalities and ventricular arrhythmias of left ventricular origin were also provided. This article reviews the evolving approach to diagnosis of ACM, going back to the 1994 and 2010 International Task Force criteria and then grapple with the modern 2020 International criteria.Domenico CorradoAlessandro ZorziAlberto CiprianiBarbara BauceRiccardo BarianiGiorgia BeffagnaManuel De LazzariFederico MiglioreKalliopi PilichouAlessandra RampazzoIlaria RigatoStefania RizzoGaetano ThieneMartina Perazzolo MarraCristina BassoWileyarticlecardiac magnetic resonancecardiomyopathydiagnosissudden deathventricular arrhythmiaDiseases of the circulatory (Cardiovascular) systemRC666-701ENJournal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 10, Iss 18 (2021) |
institution |
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collection |
DOAJ |
language |
EN |
topic |
cardiac magnetic resonance cardiomyopathy diagnosis sudden death ventricular arrhythmia Diseases of the circulatory (Cardiovascular) system RC666-701 |
spellingShingle |
cardiac magnetic resonance cardiomyopathy diagnosis sudden death ventricular arrhythmia Diseases of the circulatory (Cardiovascular) system RC666-701 Domenico Corrado Alessandro Zorzi Alberto Cipriani Barbara Bauce Riccardo Bariani Giorgia Beffagna Manuel De Lazzari Federico Migliore Kalliopi Pilichou Alessandra Rampazzo Ilaria Rigato Stefania Rizzo Gaetano Thiene Martina Perazzolo Marra Cristina Basso Evolving Diagnostic Criteria for Arrhythmogenic Cardiomyopathy |
description |
Abstract Criteria for diagnosis of arrhythmogenic cardiomyopathy (ACM) were first proposed in 1994 and revised in 2010 by a Task Force. Although the Task Force criteria demonstrated a good accuracy for diagnosis of the original right ventricular phenotype (arrhythmogenic right ventricular cardiomyopathy), they lacked sensitivity for identification of the expanding phenotypic spectrum of ACM, which includes left‐sided variants and did not incorporate late‐gadolinium enhancement findings by cardiac magnetic resonance. The 2020 International criteria (“Padua criteria”) have been developed by International experts with the aim to improve the diagnosis of ACM by providing new criteria for the diagnosis of left ventricular phenotypic features. The key upgrade was the incorporation of tissue characterization findings by cardiac magnetic resonance for noninvasive detection of late‐gadolinium enhancement/myocardial fibrosis that are determinants for characterization of arrhythmogenic biventricular and left ventricular cardiomyopathy. The 2020 International criteria are heavily dependent on cardiac magnetic resonance, which has become mandatory to characterize the ACM phenotype and to exclude other diagnoses. New criteria regarding left ventricular depolarization and repolarization ECG abnormalities and ventricular arrhythmias of left ventricular origin were also provided. This article reviews the evolving approach to diagnosis of ACM, going back to the 1994 and 2010 International Task Force criteria and then grapple with the modern 2020 International criteria. |
format |
article |
author |
Domenico Corrado Alessandro Zorzi Alberto Cipriani Barbara Bauce Riccardo Bariani Giorgia Beffagna Manuel De Lazzari Federico Migliore Kalliopi Pilichou Alessandra Rampazzo Ilaria Rigato Stefania Rizzo Gaetano Thiene Martina Perazzolo Marra Cristina Basso |
author_facet |
Domenico Corrado Alessandro Zorzi Alberto Cipriani Barbara Bauce Riccardo Bariani Giorgia Beffagna Manuel De Lazzari Federico Migliore Kalliopi Pilichou Alessandra Rampazzo Ilaria Rigato Stefania Rizzo Gaetano Thiene Martina Perazzolo Marra Cristina Basso |
author_sort |
Domenico Corrado |
title |
Evolving Diagnostic Criteria for Arrhythmogenic Cardiomyopathy |
title_short |
Evolving Diagnostic Criteria for Arrhythmogenic Cardiomyopathy |
title_full |
Evolving Diagnostic Criteria for Arrhythmogenic Cardiomyopathy |
title_fullStr |
Evolving Diagnostic Criteria for Arrhythmogenic Cardiomyopathy |
title_full_unstemmed |
Evolving Diagnostic Criteria for Arrhythmogenic Cardiomyopathy |
title_sort |
evolving diagnostic criteria for arrhythmogenic cardiomyopathy |
publisher |
Wiley |
publishDate |
2021 |
url |
https://doaj.org/article/37bbe4398dd24249a34002d7ee2e8e2f |
work_keys_str_mv |
AT domenicocorrado evolvingdiagnosticcriteriaforarrhythmogeniccardiomyopathy AT alessandrozorzi evolvingdiagnosticcriteriaforarrhythmogeniccardiomyopathy AT albertocipriani evolvingdiagnosticcriteriaforarrhythmogeniccardiomyopathy AT barbarabauce evolvingdiagnosticcriteriaforarrhythmogeniccardiomyopathy AT riccardobariani evolvingdiagnosticcriteriaforarrhythmogeniccardiomyopathy AT giorgiabeffagna evolvingdiagnosticcriteriaforarrhythmogeniccardiomyopathy AT manueldelazzari evolvingdiagnosticcriteriaforarrhythmogeniccardiomyopathy AT federicomigliore evolvingdiagnosticcriteriaforarrhythmogeniccardiomyopathy AT kalliopipilichou evolvingdiagnosticcriteriaforarrhythmogeniccardiomyopathy AT alessandrarampazzo evolvingdiagnosticcriteriaforarrhythmogeniccardiomyopathy AT ilariarigato evolvingdiagnosticcriteriaforarrhythmogeniccardiomyopathy AT stefaniarizzo evolvingdiagnosticcriteriaforarrhythmogeniccardiomyopathy AT gaetanothiene evolvingdiagnosticcriteriaforarrhythmogeniccardiomyopathy AT martinaperazzolomarra evolvingdiagnosticcriteriaforarrhythmogeniccardiomyopathy AT cristinabasso evolvingdiagnosticcriteriaforarrhythmogeniccardiomyopathy |
_version_ |
1718416756438990848 |