Opposite feedback from mTORC1 to H-ras and K-ras4B downstream of SREBP1

Abstract As a major growth factor transducer, Ras is an upstream activator of mTORC1, which further integrates nutrient and energy inputs. To ensure a contextual coupling of cell division via Ras/MAPK-signalling and growth via mTORC1-signalling, feedback loops from one pathway back to the other are...

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Autores principales: Itziar M. D. Posada, Benoit Lectez, Farid A. Siddiqui, Christina Oetken-Lindholm, Mukund Sharma, Daniel Abankwa
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2017
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Acceso en línea:https://doaj.org/article/37bdb60d533147c484ba87879ea57fcb
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