Retinol saturase coordinates liver metabolism by regulating ChREBP activity

Fatty liver is one of the major features of metabolic syndrome and its development is associated with deregulation of systemic lipid and glucose homeostasis. Here Heidenreich et al. show that retinol saturase is implicated in hepatic lipid metabolism by regulating the activity of the transcription f...

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Autores principales:	Steffi Heidenreich, Nicole Witte, Pamela Weber, Isabel Goehring, Alexander Tolkachov, Christian von Loeffelholz, Stephanie Döcke, Michael Bauer, Martin Stockmann, Andreas F. H. Pfeiffer, Andreas L. Birkenfeld, Matthias Pietzke, Stefan Kempa, Matthias Muenzner, Michael Schupp
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2017
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/37c1221ca2244b489f045cd0721ad8d4
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spelling	oai:doaj.org-article:37c1221ca2244b489f045cd0721ad8d42021-12-02T14:42:55ZRetinol saturase coordinates liver metabolism by regulating ChREBP activity10.1038/s41467-017-00430-w2041-1723https://doaj.org/article/37c1221ca2244b489f045cd0721ad8d42017-08-01T00:00:00Zhttps://doi.org/10.1038/s41467-017-00430-whttps://doaj.org/toc/2041-1723Fatty liver is one of the major features of metabolic syndrome and its development is associated with deregulation of systemic lipid and glucose homeostasis. Here Heidenreich et al. show that retinol saturase is implicated in hepatic lipid metabolism by regulating the activity of the transcription factor ChREBP.Steffi HeidenreichNicole WittePamela WeberIsabel GoehringAlexander TolkachovChristian von LoeffelholzStephanie DöckeMichael BauerMartin StockmannAndreas F. H. PfeifferAndreas L. BirkenfeldMatthias PietzkeStefan KempaMatthias MuenznerMichael SchuppNature PortfolioarticleScienceQENNature Communications, Vol 8, Iss 1, Pp 1-10 (2017)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Steffi Heidenreich Nicole Witte Pamela Weber Isabel Goehring Alexander Tolkachov Christian von Loeffelholz Stephanie Döcke Michael Bauer Martin Stockmann Andreas F. H. Pfeiffer Andreas L. Birkenfeld Matthias Pietzke Stefan Kempa Matthias Muenzner Michael Schupp Retinol saturase coordinates liver metabolism by regulating ChREBP activity
description	Fatty liver is one of the major features of metabolic syndrome and its development is associated with deregulation of systemic lipid and glucose homeostasis. Here Heidenreich et al. show that retinol saturase is implicated in hepatic lipid metabolism by regulating the activity of the transcription factor ChREBP.
format	article
author	Steffi Heidenreich Nicole Witte Pamela Weber Isabel Goehring Alexander Tolkachov Christian von Loeffelholz Stephanie Döcke Michael Bauer Martin Stockmann Andreas F. H. Pfeiffer Andreas L. Birkenfeld Matthias Pietzke Stefan Kempa Matthias Muenzner Michael Schupp
author_facet	Steffi Heidenreich Nicole Witte Pamela Weber Isabel Goehring Alexander Tolkachov Christian von Loeffelholz Stephanie Döcke Michael Bauer Martin Stockmann Andreas F. H. Pfeiffer Andreas L. Birkenfeld Matthias Pietzke Stefan Kempa Matthias Muenzner Michael Schupp
author_sort	Steffi Heidenreich
title	Retinol saturase coordinates liver metabolism by regulating ChREBP activity
title_short	Retinol saturase coordinates liver metabolism by regulating ChREBP activity
title_full	Retinol saturase coordinates liver metabolism by regulating ChREBP activity
title_fullStr	Retinol saturase coordinates liver metabolism by regulating ChREBP activity
title_full_unstemmed	Retinol saturase coordinates liver metabolism by regulating ChREBP activity
title_sort	retinol saturase coordinates liver metabolism by regulating chrebp activity
publisher	Nature Portfolio
publishDate	2017
url	https://doaj.org/article/37c1221ca2244b489f045cd0721ad8d4
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_version_	1718389559858823168

Retinol saturase coordinates liver metabolism by regulating ChREBP activity

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