Single-cell transcriptomic analysis in a mouse model deciphers cell transition states in the multistep development of esophageal cancer

The multistep processes involved in the evolution of inflammation to invasive esophageal squamous cell carcinoma (ESCC) is unclear. Here, the authors report a mouse model of ESCC and the role of interplay between carcinogen-transformed epithelial cells and their microenvironment in ESCC development.

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Autores principales:	Jiacheng Yao, Qionghua Cui, Wenyi Fan, Yuling Ma, Yamei Chen, Tianyuan Liu, Xiannian Zhang, Yiyi Xi, Chengcheng Wang, Linna Peng, Yingying Luo, Ai Lin, Wenjia Guo, Lin Lin, Yuan Lin, Wen Tan, Dongxin Lin, Chen Wu, Jianbin Wang
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2020
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/37cc999bc41b4082b5c5f89652f95a3b
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!

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spelling	oai:doaj.org-article:37cc999bc41b4082b5c5f89652f95a3b2021-12-02T17:55:14ZSingle-cell transcriptomic analysis in a mouse model deciphers cell transition states in the multistep development of esophageal cancer10.1038/s41467-020-17492-y2041-1723https://doaj.org/article/37cc999bc41b4082b5c5f89652f95a3b2020-07-01T00:00:00Zhttps://doi.org/10.1038/s41467-020-17492-yhttps://doaj.org/toc/2041-1723The multistep processes involved in the evolution of inflammation to invasive esophageal squamous cell carcinoma (ESCC) is unclear. Here, the authors report a mouse model of ESCC and the role of interplay between carcinogen-transformed epithelial cells and their microenvironment in ESCC development.Jiacheng YaoQionghua CuiWenyi FanYuling MaYamei ChenTianyuan LiuXiannian ZhangYiyi XiChengcheng WangLinna PengYingying LuoAi LinWenjia GuoLin LinYuan LinWen TanDongxin LinChen WuJianbin WangNature PortfolioarticleScienceQENNature Communications, Vol 11, Iss 1, Pp 1-13 (2020)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Jiacheng Yao Qionghua Cui Wenyi Fan Yuling Ma Yamei Chen Tianyuan Liu Xiannian Zhang Yiyi Xi Chengcheng Wang Linna Peng Yingying Luo Ai Lin Wenjia Guo Lin Lin Yuan Lin Wen Tan Dongxin Lin Chen Wu Jianbin Wang Single-cell transcriptomic analysis in a mouse model deciphers cell transition states in the multistep development of esophageal cancer
description	The multistep processes involved in the evolution of inflammation to invasive esophageal squamous cell carcinoma (ESCC) is unclear. Here, the authors report a mouse model of ESCC and the role of interplay between carcinogen-transformed epithelial cells and their microenvironment in ESCC development.
format	article
author	Jiacheng Yao Qionghua Cui Wenyi Fan Yuling Ma Yamei Chen Tianyuan Liu Xiannian Zhang Yiyi Xi Chengcheng Wang Linna Peng Yingying Luo Ai Lin Wenjia Guo Lin Lin Yuan Lin Wen Tan Dongxin Lin Chen Wu Jianbin Wang
author_facet	Jiacheng Yao Qionghua Cui Wenyi Fan Yuling Ma Yamei Chen Tianyuan Liu Xiannian Zhang Yiyi Xi Chengcheng Wang Linna Peng Yingying Luo Ai Lin Wenjia Guo Lin Lin Yuan Lin Wen Tan Dongxin Lin Chen Wu Jianbin Wang
author_sort	Jiacheng Yao
title	Single-cell transcriptomic analysis in a mouse model deciphers cell transition states in the multistep development of esophageal cancer
title_short	Single-cell transcriptomic analysis in a mouse model deciphers cell transition states in the multistep development of esophageal cancer
title_full	Single-cell transcriptomic analysis in a mouse model deciphers cell transition states in the multistep development of esophageal cancer
title_fullStr	Single-cell transcriptomic analysis in a mouse model deciphers cell transition states in the multistep development of esophageal cancer
title_full_unstemmed	Single-cell transcriptomic analysis in a mouse model deciphers cell transition states in the multistep development of esophageal cancer
title_sort	single-cell transcriptomic analysis in a mouse model deciphers cell transition states in the multistep development of esophageal cancer
publisher	Nature Portfolio
publishDate	2020
url	https://doaj.org/article/37cc999bc41b4082b5c5f89652f95a3b
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Single-cell transcriptomic analysis in a mouse model deciphers cell transition states in the multistep development of esophageal cancer

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