Pb(II) Induces Scramblase Activation and Ceramide-Domain Generation in Red Blood Cells

Pb(II) Induces Scramblase Activation and Ceramide-Domain Generation in Red Blood Cells

Abstract The mechanisms of Pb(II) toxicity have been studied in human red blood cells using confocal microscopy, immunolabeling, fluorescence-activated cell sorting and atomic force microscopy. The process follows a sequence of events, starting with calcium entry, followed by potassium release, morp...

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Main Authors: Hasna Ahyayauch, Aritz B. García-Arribas, Jesús Sot, Emilio J. González-Ramírez, Jon V. Busto, Bingen G. Monasterio, Noemi Jiménez-Rojo, F. Xabier Contreras, Adela Rendón-Ramírez, Cesar Martin, Alicia Alonso, Félix M. Goñi
Format: article
Language:EN
Published: Nature Portfolio 2018
Subjects:
Medicine
R
Science
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Online Access:https://doaj.org/article/37d7248c8b5a44c8b4b2d7778320e8bc
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https://doaj.org/article/37d7248c8b5a44c8b4b2d7778320e8bc

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