Pb(II) Induces Scramblase Activation and Ceramide-Domain Generation in Red Blood Cells
Abstract The mechanisms of Pb(II) toxicity have been studied in human red blood cells using confocal microscopy, immunolabeling, fluorescence-activated cell sorting and atomic force microscopy. The process follows a sequence of events, starting with calcium entry, followed by potassium release, morp...
Saved in:
Main Authors: | Hasna Ahyayauch, Aritz B. García-Arribas, Jesús Sot, Emilio J. González-Ramírez, Jon V. Busto, Bingen G. Monasterio, Noemi Jiménez-Rojo, F. Xabier Contreras, Adela Rendón-Ramírez, Cesar Martin, Alicia Alonso, Félix M. Goñi |
---|---|
Format: | article |
Language: | EN |
Published: |
Nature Portfolio
2018
|
Subjects: | |
Online Access: | https://doaj.org/article/37d7248c8b5a44c8b4b2d7778320e8bc |
Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
Similar Items
-
Gating and Regulatory Mechanisms of TMEM16 Ion Channels and Scramblases
by: Son C. Le, et al.
Published: (2021) -
Molecular mechanisms of ion conduction and ion selectivity in TMEM16 lipid scramblases
by: Andrei Y. Kostritskii, et al.
Published: (2021) -
Gating mechanism of the extracellular entry to the lipid pathway in a TMEM16 scramblase
by: Byoung-Cheol Lee, et al.
Published: (2018) -
The structural basis of lipid scrambling and inactivation in the endoplasmic reticulum scramblase TMEM16K
by: Simon R. Bushell, et al.
Published: (2019) -
Ceramide Remodeling and Risk of Cardiovascular Events and Mortality
by: Linda R. Peterson, et al.
Published: (2018)