Connection between genetic and clinical data in bipolar disorder.

Complex diseases may be associated with combinations of changes in DNA, where the single change has little impact alone. In a previous study of patients with bipolar disorder and controls combinations of SNP genotypes were analyzed, and four large clusters of combinations were found to be significan...

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Autores principales:	Erling Mellerup, Ole Andreassen, Bente Bennike, Henrik Dam, Srdjan Djurovic, Thomas Hansen, Ingrid Melle, Gert Lykke Møller, Ole Mors, Pernille Koefoed
Formato:	article
Lenguaje:	EN
Publicado:	Public Library of Science (PLoS) 2012
Materias:	Medicine R Science Q
Acceso en línea:	https://doaj.org/article/37d78f7431f44d15ae0dd299fe40d5f2
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spelling	oai:doaj.org-article:37d78f7431f44d15ae0dd299fe40d5f22021-11-18T07:04:49ZConnection between genetic and clinical data in bipolar disorder.1932-620310.1371/journal.pone.0044623https://doaj.org/article/37d78f7431f44d15ae0dd299fe40d5f22012-01-01T00:00:00Zhttps://www.ncbi.nlm.nih.gov/pmc/articles/pmid/23028568/?tool=EBIhttps://doaj.org/toc/1932-6203Complex diseases may be associated with combinations of changes in DNA, where the single change has little impact alone. In a previous study of patients with bipolar disorder and controls combinations of SNP genotypes were analyzed, and four large clusters of combinations were found to be significantly associated with bipolar disorder. It has now been found that these clusters may be connected to clinical data.Erling MellerupOle AndreassenBente BennikeHenrik DamSrdjan DjurovicThomas HansenIngrid MelleGert Lykke MøllerOle MorsPernille KoefoedPublic Library of Science (PLoS)articleMedicineRScienceQENPLoS ONE, Vol 7, Iss 9, p e44623 (2012)
institution	DOAJ
collection	DOAJ
language	EN
topic	Medicine R Science Q
spellingShingle	Medicine R Science Q Erling Mellerup Ole Andreassen Bente Bennike Henrik Dam Srdjan Djurovic Thomas Hansen Ingrid Melle Gert Lykke Møller Ole Mors Pernille Koefoed Connection between genetic and clinical data in bipolar disorder.
description	Complex diseases may be associated with combinations of changes in DNA, where the single change has little impact alone. In a previous study of patients with bipolar disorder and controls combinations of SNP genotypes were analyzed, and four large clusters of combinations were found to be significantly associated with bipolar disorder. It has now been found that these clusters may be connected to clinical data.
format	article
author	Erling Mellerup Ole Andreassen Bente Bennike Henrik Dam Srdjan Djurovic Thomas Hansen Ingrid Melle Gert Lykke Møller Ole Mors Pernille Koefoed
author_facet	Erling Mellerup Ole Andreassen Bente Bennike Henrik Dam Srdjan Djurovic Thomas Hansen Ingrid Melle Gert Lykke Møller Ole Mors Pernille Koefoed
author_sort	Erling Mellerup
title	Connection between genetic and clinical data in bipolar disorder.
title_short	Connection between genetic and clinical data in bipolar disorder.
title_full	Connection between genetic and clinical data in bipolar disorder.
title_fullStr	Connection between genetic and clinical data in bipolar disorder.
title_full_unstemmed	Connection between genetic and clinical data in bipolar disorder.
title_sort	connection between genetic and clinical data in bipolar disorder.
publisher	Public Library of Science (PLoS)
publishDate	2012
url	https://doaj.org/article/37d78f7431f44d15ae0dd299fe40d5f2
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Connection between genetic and clinical data in bipolar disorder.

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