BDNF rescues BAF53b-dependent synaptic plasticity and cocaine-associated memory in the nucleus accumbens

Epigenetic mechanisms play a key role in drug-associated memories and behaviors. Here authors show that mice deficient of BAF53b, a nucleosome remodeling complex subunit, display deficits in synaptic plasticity and cocaine-associated memory, both of which can be rescued by BDNF application.

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Autores principales:	André O. White, Enikö A. Kramár, Alberto J. López, Janine L. Kwapis, John Doan, David Saldana, M. Felicia Davatolhagh, Yasaman Alaghband, Mathew Blurton-Jones, Dina P. Matheos, Marcelo A. Wood
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2016
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/37dbd22580704fe786b26acb2218046b
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spelling	oai:doaj.org-article:37dbd22580704fe786b26acb2218046b2021-12-02T14:38:55ZBDNF rescues BAF53b-dependent synaptic plasticity and cocaine-associated memory in the nucleus accumbens10.1038/ncomms117252041-1723https://doaj.org/article/37dbd22580704fe786b26acb2218046b2016-05-01T00:00:00Zhttps://doi.org/10.1038/ncomms11725https://doaj.org/toc/2041-1723Epigenetic mechanisms play a key role in drug-associated memories and behaviors. Here authors show that mice deficient of BAF53b, a nucleosome remodeling complex subunit, display deficits in synaptic plasticity and cocaine-associated memory, both of which can be rescued by BDNF application.André O. WhiteEnikö A. KramárAlberto J. LópezJanine L. KwapisJohn DoanDavid SaldanaM. Felicia DavatolhaghYasaman AlaghbandMathew Blurton-JonesDina P. MatheosMarcelo A. WoodNature PortfolioarticleScienceQENNature Communications, Vol 7, Iss 1, Pp 1-12 (2016)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q André O. White Enikö A. Kramár Alberto J. López Janine L. Kwapis John Doan David Saldana M. Felicia Davatolhagh Yasaman Alaghband Mathew Blurton-Jones Dina P. Matheos Marcelo A. Wood BDNF rescues BAF53b-dependent synaptic plasticity and cocaine-associated memory in the nucleus accumbens
description	Epigenetic mechanisms play a key role in drug-associated memories and behaviors. Here authors show that mice deficient of BAF53b, a nucleosome remodeling complex subunit, display deficits in synaptic plasticity and cocaine-associated memory, both of which can be rescued by BDNF application.
format	article
author	André O. White Enikö A. Kramár Alberto J. López Janine L. Kwapis John Doan David Saldana M. Felicia Davatolhagh Yasaman Alaghband Mathew Blurton-Jones Dina P. Matheos Marcelo A. Wood
author_facet	André O. White Enikö A. Kramár Alberto J. López Janine L. Kwapis John Doan David Saldana M. Felicia Davatolhagh Yasaman Alaghband Mathew Blurton-Jones Dina P. Matheos Marcelo A. Wood
author_sort	André O. White
title	BDNF rescues BAF53b-dependent synaptic plasticity and cocaine-associated memory in the nucleus accumbens
title_short	BDNF rescues BAF53b-dependent synaptic plasticity and cocaine-associated memory in the nucleus accumbens
title_full	BDNF rescues BAF53b-dependent synaptic plasticity and cocaine-associated memory in the nucleus accumbens
title_fullStr	BDNF rescues BAF53b-dependent synaptic plasticity and cocaine-associated memory in the nucleus accumbens
title_full_unstemmed	BDNF rescues BAF53b-dependent synaptic plasticity and cocaine-associated memory in the nucleus accumbens
title_sort	bdnf rescues baf53b-dependent synaptic plasticity and cocaine-associated memory in the nucleus accumbens
publisher	Nature Portfolio
publishDate	2016
url	https://doaj.org/article/37dbd22580704fe786b26acb2218046b
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BDNF rescues BAF53b-dependent synaptic plasticity and cocaine-associated memory in the nucleus accumbens

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