Analogues of Disulfides from Allium stipitatum Demonstrate Potent Anti-tubercular Activities through Drug Efflux Pump and Biofilm Inhibition
Abstract Disulfides from Allium stipitatum, commonly known as Persian shallot, were previously reported to possess antibacterial properties. Analogues of these compounds, produced by S-methylthiolation of appropriate thiols using S-methyl methanethiosulfonate, exhibited antimicrobial activity, with...
Saved in:
Main Authors: | Cynthia A. Danquah, Eleftheria Kakagianni, Proma Khondkar, Arundhati Maitra, Mukhlesur Rahman, Dimitrios Evangelopoulos, Timothy D. McHugh, Paul Stapleton, John Malkinson, Sanjib Bhakta, Simon Gibbons |
---|---|
Format: | article |
Language: | EN |
Published: |
Nature Portfolio
2018
|
Subjects: | |
Online Access: | https://doaj.org/article/37e1ab0ec36449f69d577c41c3e6f546 |
Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
Similar Items
-
Identification of KasA as the cellular target of an anti-tubercular scaffold
by: Katherine A. Abrahams, et al.
Published: (2016) -
Anti-tubercular Activity of Pyrazinamide is Independent of trans-Translation and RpsA
by: Nicholas A. Dillon, et al.
Published: (2017) -
Diagnostic accuracy of GeneXpert MTB/RIF assay for detection of tubercular pleural effusion.
by: Jyoti Jain, et al.
Published: (2021) -
FUNCTIONAL AND METABOLIC FEATURES OF BLOOD PHAGOCYTES AT DIFFERENT FORMS OF TUBERCULAR INFLAMMATORY PROCESS OF LUNGS
by: O. V. Berdyugina, et al.
Published: (2016) -
The Impact of First-Line Anti-Tubercular Drugs’ Pharmacokinetics on Treatment Outcome: A Systematic Review
by: Sileshi T, et al.
Published: (2021)