MSH3-deficiency initiates EMAST without oncogenic transformation of human colon epithelial cells.
<h4>Background/aim</h4>Elevated microsatellite instability at selected tetranucleotide repeats (EMAST) is a genetic signature in certain cases of sporadic colorectal cancer and has been linked to MSH3-deficiency. It is currently controversial whether EMAST is associated with oncogenic pr...
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Autores principales: | Christoph Campregher, Gerald Schmid, Franziska Ferk, Siegfried Knasmüller, Vineeta Khare, Benedikt Kortüm, Kyle Dammann, Michaela Lang, Theresa Scharl, Andreas Spittler, Andres I Roig, Jerry W Shay, Christopher Gerner, Christoph Gasche |
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Formato: | article |
Lenguaje: | EN |
Publicado: |
Public Library of Science (PLoS)
2012
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Materias: | |
Acceso en línea: | https://doaj.org/article/37e4f1008a594872bb5cfd82f5c85f2d |
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