MSH3-deficiency initiates EMAST without oncogenic transformation of human colon epithelial cells.

MSH3-deficiency initiates EMAST without oncogenic transformation of human colon epithelial cells.

<h4>Background/aim</h4>Elevated microsatellite instability at selected tetranucleotide repeats (EMAST) is a genetic signature in certain cases of sporadic colorectal cancer and has been linked to MSH3-deficiency. It is currently controversial whether EMAST is associated with oncogenic pr...

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Main Authors: Christoph Campregher, Gerald Schmid, Franziska Ferk, Siegfried Knasmüller, Vineeta Khare, Benedikt Kortüm, Kyle Dammann, Michaela Lang, Theresa Scharl, Andreas Spittler, Andres I Roig, Jerry W Shay, Christopher Gerner, Christoph Gasche
Format: article
Language:EN
Published: Public Library of Science (PLoS) 2012
Subjects:
Medicine
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Science
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Online Access:https://doaj.org/article/37e4f1008a594872bb5cfd82f5c85f2d
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