Generation of pluripotent stem cell-derived mouse kidneys in Sall1-targeted anephric rats
The use of pluripotent-stem cell derived organs for transplantation would be promising, if organs can be grown in a suitable host. Here, the authors use interspecific blastocyst complementation to generate a mouse pluripotent stem cell-derived kidney in anephric Sall1 mutant rats.
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Nature Portfolio
2019
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oai:doaj.org-article:37e5f190bd684e10aa522b392a1148932021-12-02T17:31:38ZGeneration of pluripotent stem cell-derived mouse kidneys in Sall1-targeted anephric rats10.1038/s41467-019-08394-92041-1723https://doaj.org/article/37e5f190bd684e10aa522b392a1148932019-02-01T00:00:00Zhttps://doi.org/10.1038/s41467-019-08394-9https://doaj.org/toc/2041-1723The use of pluripotent-stem cell derived organs for transplantation would be promising, if organs can be grown in a suitable host. Here, the authors use interspecific blastocyst complementation to generate a mouse pluripotent stem cell-derived kidney in anephric Sall1 mutant rats.Teppei GotoHiromasa HaraMakoto SanboHideki MasakiHideyuki SatoTomoyuki YamaguchiShinichi HochiToshihiro KobayashiHiromitsu NakauchiMasumi HirabayashiNature PortfolioarticleScienceQENNature Communications, Vol 10, Iss 1, Pp 1-9 (2019) |
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Science Q Teppei Goto Hiromasa Hara Makoto Sanbo Hideki Masaki Hideyuki Sato Tomoyuki Yamaguchi Shinichi Hochi Toshihiro Kobayashi Hiromitsu Nakauchi Masumi Hirabayashi Generation of pluripotent stem cell-derived mouse kidneys in Sall1-targeted anephric rats |
description |
The use of pluripotent-stem cell derived organs for transplantation would be promising, if organs can be grown in a suitable host. Here, the authors use interspecific blastocyst complementation to generate a mouse pluripotent stem cell-derived kidney in anephric Sall1 mutant rats. |
format |
article |
author |
Teppei Goto Hiromasa Hara Makoto Sanbo Hideki Masaki Hideyuki Sato Tomoyuki Yamaguchi Shinichi Hochi Toshihiro Kobayashi Hiromitsu Nakauchi Masumi Hirabayashi |
author_facet |
Teppei Goto Hiromasa Hara Makoto Sanbo Hideki Masaki Hideyuki Sato Tomoyuki Yamaguchi Shinichi Hochi Toshihiro Kobayashi Hiromitsu Nakauchi Masumi Hirabayashi |
author_sort |
Teppei Goto |
title |
Generation of pluripotent stem cell-derived mouse kidneys in Sall1-targeted anephric rats |
title_short |
Generation of pluripotent stem cell-derived mouse kidneys in Sall1-targeted anephric rats |
title_full |
Generation of pluripotent stem cell-derived mouse kidneys in Sall1-targeted anephric rats |
title_fullStr |
Generation of pluripotent stem cell-derived mouse kidneys in Sall1-targeted anephric rats |
title_full_unstemmed |
Generation of pluripotent stem cell-derived mouse kidneys in Sall1-targeted anephric rats |
title_sort |
generation of pluripotent stem cell-derived mouse kidneys in sall1-targeted anephric rats |
publisher |
Nature Portfolio |
publishDate |
2019 |
url |
https://doaj.org/article/37e5f190bd684e10aa522b392a114893 |
work_keys_str_mv |
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