Generation of pluripotent stem cell-derived mouse kidneys in Sall1-targeted anephric rats

The use of pluripotent-stem cell derived organs for transplantation would be promising, if organs can be grown in a suitable host. Here, the authors use interspecific blastocyst complementation to generate a mouse pluripotent stem cell-derived kidney in anephric Sall1 mutant rats.

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Autores principales: Teppei Goto, Hiromasa Hara, Makoto Sanbo, Hideki Masaki, Hideyuki Sato, Tomoyuki Yamaguchi, Shinichi Hochi, Toshihiro Kobayashi, Hiromitsu Nakauchi, Masumi Hirabayashi
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Lenguaje:EN
Publicado: Nature Portfolio 2019
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Acceso en línea:https://doaj.org/article/37e5f190bd684e10aa522b392a114893
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spelling oai:doaj.org-article:37e5f190bd684e10aa522b392a1148932021-12-02T17:31:38ZGeneration of pluripotent stem cell-derived mouse kidneys in Sall1-targeted anephric rats10.1038/s41467-019-08394-92041-1723https://doaj.org/article/37e5f190bd684e10aa522b392a1148932019-02-01T00:00:00Zhttps://doi.org/10.1038/s41467-019-08394-9https://doaj.org/toc/2041-1723The use of pluripotent-stem cell derived organs for transplantation would be promising, if organs can be grown in a suitable host. Here, the authors use interspecific blastocyst complementation to generate a mouse pluripotent stem cell-derived kidney in anephric Sall1 mutant rats.Teppei GotoHiromasa HaraMakoto SanboHideki MasakiHideyuki SatoTomoyuki YamaguchiShinichi HochiToshihiro KobayashiHiromitsu NakauchiMasumi HirabayashiNature PortfolioarticleScienceQENNature Communications, Vol 10, Iss 1, Pp 1-9 (2019)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Teppei Goto
Hiromasa Hara
Makoto Sanbo
Hideki Masaki
Hideyuki Sato
Tomoyuki Yamaguchi
Shinichi Hochi
Toshihiro Kobayashi
Hiromitsu Nakauchi
Masumi Hirabayashi
Generation of pluripotent stem cell-derived mouse kidneys in Sall1-targeted anephric rats
description The use of pluripotent-stem cell derived organs for transplantation would be promising, if organs can be grown in a suitable host. Here, the authors use interspecific blastocyst complementation to generate a mouse pluripotent stem cell-derived kidney in anephric Sall1 mutant rats.
format article
author Teppei Goto
Hiromasa Hara
Makoto Sanbo
Hideki Masaki
Hideyuki Sato
Tomoyuki Yamaguchi
Shinichi Hochi
Toshihiro Kobayashi
Hiromitsu Nakauchi
Masumi Hirabayashi
author_facet Teppei Goto
Hiromasa Hara
Makoto Sanbo
Hideki Masaki
Hideyuki Sato
Tomoyuki Yamaguchi
Shinichi Hochi
Toshihiro Kobayashi
Hiromitsu Nakauchi
Masumi Hirabayashi
author_sort Teppei Goto
title Generation of pluripotent stem cell-derived mouse kidneys in Sall1-targeted anephric rats
title_short Generation of pluripotent stem cell-derived mouse kidneys in Sall1-targeted anephric rats
title_full Generation of pluripotent stem cell-derived mouse kidneys in Sall1-targeted anephric rats
title_fullStr Generation of pluripotent stem cell-derived mouse kidneys in Sall1-targeted anephric rats
title_full_unstemmed Generation of pluripotent stem cell-derived mouse kidneys in Sall1-targeted anephric rats
title_sort generation of pluripotent stem cell-derived mouse kidneys in sall1-targeted anephric rats
publisher Nature Portfolio
publishDate 2019
url https://doaj.org/article/37e5f190bd684e10aa522b392a114893
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