Generation of pluripotent stem cell-derived mouse kidneys in Sall1-targeted anephric rats

The use of pluripotent-stem cell derived organs for transplantation would be promising, if organs can be grown in a suitable host. Here, the authors use interspecific blastocyst complementation to generate a mouse pluripotent stem cell-derived kidney in anephric Sall1 mutant rats.

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Autores principales: Teppei Goto, Hiromasa Hara, Makoto Sanbo, Hideki Masaki, Hideyuki Sato, Tomoyuki Yamaguchi, Shinichi Hochi, Toshihiro Kobayashi, Hiromitsu Nakauchi, Masumi Hirabayashi
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2019
Materias:
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Acceso en línea:https://doaj.org/article/37e5f190bd684e10aa522b392a114893
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