INK4/ARF transcript expression is associated with chromosome 9p21 variants linked to atherosclerosis.

INK4/ARF transcript expression is associated with chromosome 9p21 variants linked to atherosclerosis.

<h4>Background</h4>Genome-wide association studies (GWAS) have linked common single nucleotide polymorphisms (SNPs) on chromosome 9p21 near the INK4/ARF (CDKN2A/B) tumor suppressor locus with risk of atherosclerotic diseases and type 2 diabetes mellitus. To explore the mechanism of this...

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Autores principales: Yan Liu, Hanna K Sanoff, Hyunsoon Cho, Christin E Burd, Chad Torrice, Karen L Mohlke, Joseph G Ibrahim, Nancy E Thomas, Norman E Sharpless
Formato: article
Lenguaje:EN
Publicado: Public Library of Science (PLoS) 2009
Materias:
Medicine
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Science
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Acceso en línea:https://doaj.org/article/37e7e80ef505417bac949e65119c4be0
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