Research Progress on CircRNA in Liquid Biopsy of Gastric Cancer

Gastric cancer has become a major public health problem in China because of its high prevalence. CircRNA could stably exist in various human body fluids, providing the innate advantage for the liquid biopsy, which makes it a research hotspot in the field of precision therapy in recent years. Based o...

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Autores principales: ZHU Hao, JIA Jianchao, YU Lan
Formato: article
Lenguaje:ZH
Publicado: Magazine House of Cancer Research on Prevention and Treatment 2021
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Acceso en línea:https://doaj.org/article/37f8f151139644d4919f414dcaf429e0
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spelling oai:doaj.org-article:37f8f151139644d4919f414dcaf429e02021-12-03T09:25:17ZResearch Progress on CircRNA in Liquid Biopsy of Gastric Cancer1000-857810.3971/j.issn.1000-8578.2021.21.0517https://doaj.org/article/37f8f151139644d4919f414dcaf429e02021-11-01T00:00:00Zhttp://www.zlfzyj.com/EN/10.3971/j.issn.1000-8578.2021.21.0517https://doaj.org/toc/1000-8578Gastric cancer has become a major public health problem in China because of its high prevalence. CircRNA could stably exist in various human body fluids, providing the innate advantage for the liquid biopsy, which makes it a research hotspot in the field of precision therapy in recent years. Based on the biological characteristics of circRNAs, we summarize the research progress of circRNAs in the early diagnosis, treatment monitoring and prognosis assessment of gastric cancer through literature retrieval in mainstream databases such as PubMed, Web of Science and CNKI. We also discuss the possibility and reliability of circRNA as an emerging liquid biopsy biomarker, to offer a vision for the development and clinical transformation of circRNA as a molecular marker of the diagnosis, treatment, evaluation and prognosis of gastric cancer in the future.ZHU HaoJIA JianchaoYU LanMagazine House of Cancer Research on Prevention and Treatmentarticlecircrnaliquid biopsyexosomegastric cancerNeoplasms. Tumors. Oncology. Including cancer and carcinogensRC254-282ZHZhongliu Fangzhi Yanjiu, Vol 48, Iss 11, Pp 1023-1029 (2021)
institution DOAJ
collection DOAJ
language ZH
topic circrna
liquid biopsy
exosome
gastric cancer
Neoplasms. Tumors. Oncology. Including cancer and carcinogens
RC254-282
spellingShingle circrna
liquid biopsy
exosome
gastric cancer
Neoplasms. Tumors. Oncology. Including cancer and carcinogens
RC254-282
ZHU Hao
JIA Jianchao
YU Lan
Research Progress on CircRNA in Liquid Biopsy of Gastric Cancer
description Gastric cancer has become a major public health problem in China because of its high prevalence. CircRNA could stably exist in various human body fluids, providing the innate advantage for the liquid biopsy, which makes it a research hotspot in the field of precision therapy in recent years. Based on the biological characteristics of circRNAs, we summarize the research progress of circRNAs in the early diagnosis, treatment monitoring and prognosis assessment of gastric cancer through literature retrieval in mainstream databases such as PubMed, Web of Science and CNKI. We also discuss the possibility and reliability of circRNA as an emerging liquid biopsy biomarker, to offer a vision for the development and clinical transformation of circRNA as a molecular marker of the diagnosis, treatment, evaluation and prognosis of gastric cancer in the future.
format article
author ZHU Hao
JIA Jianchao
YU Lan
author_facet ZHU Hao
JIA Jianchao
YU Lan
author_sort ZHU Hao
title Research Progress on CircRNA in Liquid Biopsy of Gastric Cancer
title_short Research Progress on CircRNA in Liquid Biopsy of Gastric Cancer
title_full Research Progress on CircRNA in Liquid Biopsy of Gastric Cancer
title_fullStr Research Progress on CircRNA in Liquid Biopsy of Gastric Cancer
title_full_unstemmed Research Progress on CircRNA in Liquid Biopsy of Gastric Cancer
title_sort research progress on circrna in liquid biopsy of gastric cancer
publisher Magazine House of Cancer Research on Prevention and Treatment
publishDate 2021
url https://doaj.org/article/37f8f151139644d4919f414dcaf429e0
work_keys_str_mv AT zhuhao researchprogressoncircrnainliquidbiopsyofgastriccancer
AT jiajianchao researchprogressoncircrnainliquidbiopsyofgastriccancer
AT yulan researchprogressoncircrnainliquidbiopsyofgastriccancer
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