Up-Regulation of p53/miR-628-3p Pathway, a Novel Mechanism of Shikonin on Inhibiting Proliferation and Inducing Apoptosis of A549 and PC-9 Non–Small Cell Lung Cancer Cell Lines

Shikonin (SHK) is a pleiotropic agent with remarkable cell growth inhibition activity against various cancer types, especially non–small cell lung cancer (NSCLC), but its molecular mechanism is still unclear. Our previous study found that miR-628-3p could inhibit the growth of A549 cells and induce...

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Bibliographic Details
Main Authors: Jieli Pan, Meiya Li, Fenglin Yu, Feiye Zhu, Linyan Wang, Dandan Ning, Xiaoli Hou, Fusheng Jiang
Format: article
Language:EN
Published: Frontiers Media S.A. 2021
Subjects:
p53
Online Access:https://doaj.org/article/37f8f2e0ccb14e8dafed70c71211a9dc
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