The tight junction protein TJP1 regulates the feeding-modulated hepatic circadian clock

The circadian clock regulates rhythms of physiology and metabolism in response to environmental cues such as food intake. Here, the authors show that tight junction protein 1 (TJP1) interacts with period 1 and modulates its nuclear translocation in a mTOR-dependent manner.

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Autores principales:	Yi Liu, Yuanyuan Zhang, Tong Li, Jinbo Han, Yiguo Wang
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2020
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/37f9ac0b72c64340ab9b1c2bcfe00ca2
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spelling	oai:doaj.org-article:37f9ac0b72c64340ab9b1c2bcfe00ca22021-12-02T17:32:14ZThe tight junction protein TJP1 regulates the feeding-modulated hepatic circadian clock10.1038/s41467-020-14470-22041-1723https://doaj.org/article/37f9ac0b72c64340ab9b1c2bcfe00ca22020-01-01T00:00:00Zhttps://doi.org/10.1038/s41467-020-14470-2https://doaj.org/toc/2041-1723The circadian clock regulates rhythms of physiology and metabolism in response to environmental cues such as food intake. Here, the authors show that tight junction protein 1 (TJP1) interacts with period 1 and modulates its nuclear translocation in a mTOR-dependent manner.Yi LiuYuanyuan ZhangTong LiJinbo HanYiguo WangNature PortfolioarticleScienceQENNature Communications, Vol 11, Iss 1, Pp 1-11 (2020)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Yi Liu Yuanyuan Zhang Tong Li Jinbo Han Yiguo Wang The tight junction protein TJP1 regulates the feeding-modulated hepatic circadian clock
description	The circadian clock regulates rhythms of physiology and metabolism in response to environmental cues such as food intake. Here, the authors show that tight junction protein 1 (TJP1) interacts with period 1 and modulates its nuclear translocation in a mTOR-dependent manner.
format	article
author	Yi Liu Yuanyuan Zhang Tong Li Jinbo Han Yiguo Wang
author_facet	Yi Liu Yuanyuan Zhang Tong Li Jinbo Han Yiguo Wang
author_sort	Yi Liu
title	The tight junction protein TJP1 regulates the feeding-modulated hepatic circadian clock
title_short	The tight junction protein TJP1 regulates the feeding-modulated hepatic circadian clock
title_full	The tight junction protein TJP1 regulates the feeding-modulated hepatic circadian clock
title_fullStr	The tight junction protein TJP1 regulates the feeding-modulated hepatic circadian clock
title_full_unstemmed	The tight junction protein TJP1 regulates the feeding-modulated hepatic circadian clock
title_sort	tight junction protein tjp1 regulates the feeding-modulated hepatic circadian clock
publisher	Nature Portfolio
publishDate	2020
url	https://doaj.org/article/37f9ac0b72c64340ab9b1c2bcfe00ca2
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The tight junction protein TJP1 regulates the feeding-modulated hepatic circadian clock

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