3-Phenylcoumarins as a Privileged Scaffold in Medicinal Chemistry: The Landmarks of the Past Decade

3-Phenylcoumarins are a family of heterocyclic molecules that are widely used in both organic and medicinal chemistry. In this overview, research on this scaffold, since 2010, is included and discussed, focusing on aspects related to its natural origin, synthetic procedures and pharmacological appli...

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Autores principales: Maria J. Matos, Eugenio Uriarte, Lourdes Santana
Formato: article
Lenguaje:EN
Publicado: MDPI AG 2021
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Acceso en línea:https://doaj.org/article/3800de983f0045f89c97447fdddb0ee1
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spelling oai:doaj.org-article:3800de983f0045f89c97447fdddb0ee12021-11-11T18:41:03Z3-Phenylcoumarins as a Privileged Scaffold in Medicinal Chemistry: The Landmarks of the Past Decade10.3390/molecules262167551420-3049https://doaj.org/article/3800de983f0045f89c97447fdddb0ee12021-11-01T00:00:00Zhttps://www.mdpi.com/1420-3049/26/21/6755https://doaj.org/toc/1420-30493-Phenylcoumarins are a family of heterocyclic molecules that are widely used in both organic and medicinal chemistry. In this overview, research on this scaffold, since 2010, is included and discussed, focusing on aspects related to its natural origin, synthetic procedures and pharmacological applications. This review paper is based on the most relevant literature related to the role of 3-phenylcoumarins in the design of new drug candidates. The references presented in this review have been collected from multiple electronic databases, including SciFinder, Pubmed and Mendeley.Maria J. MatosEugenio UriarteLourdes SantanaMDPI AGarticle3-phenylcoumarinssynthetic pathwayspharmacological activityOrganic chemistryQD241-441ENMolecules, Vol 26, Iss 6755, p 6755 (2021)
institution DOAJ
collection DOAJ
language EN
topic 3-phenylcoumarins
synthetic pathways
pharmacological activity
Organic chemistry
QD241-441
spellingShingle 3-phenylcoumarins
synthetic pathways
pharmacological activity
Organic chemistry
QD241-441
Maria J. Matos
Eugenio Uriarte
Lourdes Santana
3-Phenylcoumarins as a Privileged Scaffold in Medicinal Chemistry: The Landmarks of the Past Decade
description 3-Phenylcoumarins are a family of heterocyclic molecules that are widely used in both organic and medicinal chemistry. In this overview, research on this scaffold, since 2010, is included and discussed, focusing on aspects related to its natural origin, synthetic procedures and pharmacological applications. This review paper is based on the most relevant literature related to the role of 3-phenylcoumarins in the design of new drug candidates. The references presented in this review have been collected from multiple electronic databases, including SciFinder, Pubmed and Mendeley.
format article
author Maria J. Matos
Eugenio Uriarte
Lourdes Santana
author_facet Maria J. Matos
Eugenio Uriarte
Lourdes Santana
author_sort Maria J. Matos
title 3-Phenylcoumarins as a Privileged Scaffold in Medicinal Chemistry: The Landmarks of the Past Decade
title_short 3-Phenylcoumarins as a Privileged Scaffold in Medicinal Chemistry: The Landmarks of the Past Decade
title_full 3-Phenylcoumarins as a Privileged Scaffold in Medicinal Chemistry: The Landmarks of the Past Decade
title_fullStr 3-Phenylcoumarins as a Privileged Scaffold in Medicinal Chemistry: The Landmarks of the Past Decade
title_full_unstemmed 3-Phenylcoumarins as a Privileged Scaffold in Medicinal Chemistry: The Landmarks of the Past Decade
title_sort 3-phenylcoumarins as a privileged scaffold in medicinal chemistry: the landmarks of the past decade
publisher MDPI AG
publishDate 2021
url https://doaj.org/article/3800de983f0045f89c97447fdddb0ee1
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AT eugeniouriarte 3phenylcoumarinsasaprivilegedscaffoldinmedicinalchemistrythelandmarksofthepastdecade
AT lourdessantana 3phenylcoumarinsasaprivilegedscaffoldinmedicinalchemistrythelandmarksofthepastdecade
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