Histo-epidemiological aspect of Helicobacter pylori chronic gastritis in a Moroccan population

Helicobacter pylori (H. Pylori) is the best example of the implication of chronical infection in carcinogenesis. The World Health Organization recognized it as a class I carcinogen since it triggers the progression of premalignant gastric lesions. The aim of this study is to define the prevalence of...

Descripción completa

Guardado en:

Detalles Bibliográficos
Autores principales:	El Gui Radia, Hechlaf Hajar, Ed-Day Soumia, Akhouayri Omar, Boulbaroud Samira, Azzaoui Fatima-Zahra
Formato:	article
Lenguaje:	EN FR
Publicado:	EDP Sciences 2021
Materias:	helicobacter pylori chronic gastritis precancerous lesions epidemiology morocco Environmental sciences GE1-350
Acceso en línea:	https://doaj.org/article/380ba4d2afa2427eb1ebcddbff95114e
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!

id	oai:doaj.org-article:380ba4d2afa2427eb1ebcddbff95114e
record_format	dspace
spelling	oai:doaj.org-article:380ba4d2afa2427eb1ebcddbff95114e2021-11-12T11:44:08ZHisto-epidemiological aspect of Helicobacter pylori chronic gastritis in a Moroccan population2267-124210.1051/e3sconf/202131901027https://doaj.org/article/380ba4d2afa2427eb1ebcddbff95114e2021-01-01T00:00:00Zhttps://www.e3s-conferences.org/articles/e3sconf/pdf/2021/95/e3sconf_vigisan_01027.pdfhttps://doaj.org/toc/2267-1242Helicobacter pylori (H. Pylori) is the best example of the implication of chronical infection in carcinogenesis. The World Health Organization recognized it as a class I carcinogen since it triggers the progression of premalignant gastric lesions. The aim of this study is to define the prevalence of H. Pylori infection, related risk factors, and explore the histological features of the chronic gastritis. This is a retrospective study of 248 gastric specimens, examinated and evaluated according Sydney to system. The prevalence of H. Pylori is 67 %, chronic gastritis is observed in all the biopsies (100%). Age and gender were not a risk factors for the H. Pylori infection. Prevalence of H. Pylori was 71.93% in low socio-economic class. The severity of the chronic gastritis increases if the colonization of H. Pylori increases. In 74, 58% of cases chronic gastritis was active. Glandular atrophy presented 10.37% and in 80% was related to H. Pylori infection (p=0,004) and 12 % related to autoimmune diseases. The prevalence of Intestinal metaplasia is 10.53%, and H. Pylori was observed in 42.31% of cases (p=0.001). The dysplasia is detected in one case, in a 72 years old patient. We also observed one case of gastric adenocarcinoma, of an 80 years. Follicular gastritis are in 32% of cases, and they were more frequent in H. Pylori infected slides (82% of subjects) (p< 0.005).According to this study, H. Pylori Chronic Gastritis is very common in our population, and a coherent relationship exists between H. Pylori colonization and pre-cancerous lesions. An early eradicating should be considered as a health goal.El Gui RadiaHechlaf HajarEd-Day SoumiaAkhouayri OmarBoulbaroud SamiraAzzaoui Fatima-ZahraEDP Sciencesarticlehelicobacter pylorichronic gastritisprecancerous lesionsepidemiologymoroccoEnvironmental sciencesGE1-350ENFRE3S Web of Conferences, Vol 319, p 01027 (2021)
institution	DOAJ
collection	DOAJ
language	EN FR
topic	helicobacter pylori chronic gastritis precancerous lesions epidemiology morocco Environmental sciences GE1-350
spellingShingle	helicobacter pylori chronic gastritis precancerous lesions epidemiology morocco Environmental sciences GE1-350 El Gui Radia Hechlaf Hajar Ed-Day Soumia Akhouayri Omar Boulbaroud Samira Azzaoui Fatima-Zahra Histo-epidemiological aspect of Helicobacter pylori chronic gastritis in a Moroccan population
description	Helicobacter pylori (H. Pylori) is the best example of the implication of chronical infection in carcinogenesis. The World Health Organization recognized it as a class I carcinogen since it triggers the progression of premalignant gastric lesions. The aim of this study is to define the prevalence of H. Pylori infection, related risk factors, and explore the histological features of the chronic gastritis. This is a retrospective study of 248 gastric specimens, examinated and evaluated according Sydney to system. The prevalence of H. Pylori is 67 %, chronic gastritis is observed in all the biopsies (100%). Age and gender were not a risk factors for the H. Pylori infection. Prevalence of H. Pylori was 71.93% in low socio-economic class. The severity of the chronic gastritis increases if the colonization of H. Pylori increases. In 74, 58% of cases chronic gastritis was active. Glandular atrophy presented 10.37% and in 80% was related to H. Pylori infection (p=0,004) and 12 % related to autoimmune diseases. The prevalence of Intestinal metaplasia is 10.53%, and H. Pylori was observed in 42.31% of cases (p=0.001). The dysplasia is detected in one case, in a 72 years old patient. We also observed one case of gastric adenocarcinoma, of an 80 years. Follicular gastritis are in 32% of cases, and they were more frequent in H. Pylori infected slides (82% of subjects) (p< 0.005).According to this study, H. Pylori Chronic Gastritis is very common in our population, and a coherent relationship exists between H. Pylori colonization and pre-cancerous lesions. An early eradicating should be considered as a health goal.
format	article
author	El Gui Radia Hechlaf Hajar Ed-Day Soumia Akhouayri Omar Boulbaroud Samira Azzaoui Fatima-Zahra
author_facet	El Gui Radia Hechlaf Hajar Ed-Day Soumia Akhouayri Omar Boulbaroud Samira Azzaoui Fatima-Zahra
author_sort	El Gui Radia
title	Histo-epidemiological aspect of Helicobacter pylori chronic gastritis in a Moroccan population
title_short	Histo-epidemiological aspect of Helicobacter pylori chronic gastritis in a Moroccan population
title_full	Histo-epidemiological aspect of Helicobacter pylori chronic gastritis in a Moroccan population
title_fullStr	Histo-epidemiological aspect of Helicobacter pylori chronic gastritis in a Moroccan population
title_full_unstemmed	Histo-epidemiological aspect of Helicobacter pylori chronic gastritis in a Moroccan population
title_sort	histo-epidemiological aspect of helicobacter pylori chronic gastritis in a moroccan population
publisher	EDP Sciences
publishDate	2021
url	https://doaj.org/article/380ba4d2afa2427eb1ebcddbff95114e
work_keys_str_mv	AT elguiradia histoepidemiologicalaspectofhelicobacterpylorichronicgastritisinamoroccanpopulation AT hechlafhajar histoepidemiologicalaspectofhelicobacterpylorichronicgastritisinamoroccanpopulation AT eddaysoumia histoepidemiologicalaspectofhelicobacterpylorichronicgastritisinamoroccanpopulation AT akhouayriomar histoepidemiologicalaspectofhelicobacterpylorichronicgastritisinamoroccanpopulation AT boulbaroudsamira histoepidemiologicalaspectofhelicobacterpylorichronicgastritisinamoroccanpopulation AT azzaouifatimazahra histoepidemiologicalaspectofhelicobacterpylorichronicgastritisinamoroccanpopulation
_version_	1718430610651873280

Histo-epidemiological aspect of Helicobacter pylori chronic gastritis in a Moroccan population

Ejemplares similares