Structure and functional dynamics of the mitochondrial Fe/S cluster synthesis complex

Fe/S clusters are synthesized by the mitochondrial iron-sulfur cluster assembly (ISC) machinery. Here the authors combine crystallography and small angle X-ray scattering measurements to structurally characterize the core ISC complex and give functional insights into eukaryotic Fe/S cluster synthesi...

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Autores principales: Michal T. Boniecki, Sven A. Freibert, Ulrich Mühlenhoff, Roland Lill, Miroslaw Cygler
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2017
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Acceso en línea:https://doaj.org/article/380f33a1b9c943c18f6f4d959f2218f2
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Sumario:Fe/S clusters are synthesized by the mitochondrial iron-sulfur cluster assembly (ISC) machinery. Here the authors combine crystallography and small angle X-ray scattering measurements to structurally characterize the core ISC complex and give functional insights into eukaryotic Fe/S cluster synthesis.