The functional brain favours segregated modular connectivity at old age unless affected by neurodegeneration

Chen at al used fMRI to study the brain connectivity in two ageing cohorts and a mixed cohort of patients with neurodegenerative diseases. They demonstrated that with ageing the brain moves towards a more segregated modular structure, however this is disrupted by neurodegenerative diseases.

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Detalles Bibliográficos
Autores principales: Xue Chen, Joe Necus, Luis R. Peraza, Ramtin Mehraram, Yanjiang Wang, John T. O’Brien, Andrew Blamire, Marcus Kaiser, John-Paul Taylor
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2021
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Acceso en línea:https://doaj.org/article/3830c7bf2bbc4d73a4e49eaebe0f78a6
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Descripción
Sumario:Chen at al used fMRI to study the brain connectivity in two ageing cohorts and a mixed cohort of patients with neurodegenerative diseases. They demonstrated that with ageing the brain moves towards a more segregated modular structure, however this is disrupted by neurodegenerative diseases.