The functional brain favours segregated modular connectivity at old age unless affected by neurodegeneration
Chen at al used fMRI to study the brain connectivity in two ageing cohorts and a mixed cohort of patients with neurodegenerative diseases. They demonstrated that with ageing the brain moves towards a more segregated modular structure, however this is disrupted by neurodegenerative diseases.
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Nature Portfolio
2021
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oai:doaj.org-article:3830c7bf2bbc4d73a4e49eaebe0f78a62021-12-02T18:51:45ZThe functional brain favours segregated modular connectivity at old age unless affected by neurodegeneration10.1038/s42003-021-02497-02399-3642https://doaj.org/article/3830c7bf2bbc4d73a4e49eaebe0f78a62021-08-01T00:00:00Zhttps://doi.org/10.1038/s42003-021-02497-0https://doaj.org/toc/2399-3642Chen at al used fMRI to study the brain connectivity in two ageing cohorts and a mixed cohort of patients with neurodegenerative diseases. They demonstrated that with ageing the brain moves towards a more segregated modular structure, however this is disrupted by neurodegenerative diseases.Xue ChenJoe NecusLuis R. PerazaRamtin MehraramYanjiang WangJohn T. O’BrienAndrew BlamireMarcus KaiserJohn-Paul TaylorNature PortfolioarticleBiology (General)QH301-705.5ENCommunications Biology, Vol 4, Iss 1, Pp 1-16 (2021) |
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Biology (General) QH301-705.5 |
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Biology (General) QH301-705.5 Xue Chen Joe Necus Luis R. Peraza Ramtin Mehraram Yanjiang Wang John T. O’Brien Andrew Blamire Marcus Kaiser John-Paul Taylor The functional brain favours segregated modular connectivity at old age unless affected by neurodegeneration |
description |
Chen at al used fMRI to study the brain connectivity in two ageing cohorts and a mixed cohort of patients with neurodegenerative diseases. They demonstrated that with ageing the brain moves towards a more segregated modular structure, however this is disrupted by neurodegenerative diseases. |
format |
article |
author |
Xue Chen Joe Necus Luis R. Peraza Ramtin Mehraram Yanjiang Wang John T. O’Brien Andrew Blamire Marcus Kaiser John-Paul Taylor |
author_facet |
Xue Chen Joe Necus Luis R. Peraza Ramtin Mehraram Yanjiang Wang John T. O’Brien Andrew Blamire Marcus Kaiser John-Paul Taylor |
author_sort |
Xue Chen |
title |
The functional brain favours segregated modular connectivity at old age unless affected by neurodegeneration |
title_short |
The functional brain favours segregated modular connectivity at old age unless affected by neurodegeneration |
title_full |
The functional brain favours segregated modular connectivity at old age unless affected by neurodegeneration |
title_fullStr |
The functional brain favours segregated modular connectivity at old age unless affected by neurodegeneration |
title_full_unstemmed |
The functional brain favours segregated modular connectivity at old age unless affected by neurodegeneration |
title_sort |
functional brain favours segregated modular connectivity at old age unless affected by neurodegeneration |
publisher |
Nature Portfolio |
publishDate |
2021 |
url |
https://doaj.org/article/3830c7bf2bbc4d73a4e49eaebe0f78a6 |
work_keys_str_mv |
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