The functional brain favours segregated modular connectivity at old age unless affected by neurodegeneration

Chen at al used fMRI to study the brain connectivity in two ageing cohorts and a mixed cohort of patients with neurodegenerative diseases. They demonstrated that with ageing the brain moves towards a more segregated modular structure, however this is disrupted by neurodegenerative diseases.

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Autores principales: Xue Chen, Joe Necus, Luis R. Peraza, Ramtin Mehraram, Yanjiang Wang, John T. O’Brien, Andrew Blamire, Marcus Kaiser, John-Paul Taylor
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Lenguaje:EN
Publicado: Nature Portfolio 2021
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Acceso en línea:https://doaj.org/article/3830c7bf2bbc4d73a4e49eaebe0f78a6
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spelling oai:doaj.org-article:3830c7bf2bbc4d73a4e49eaebe0f78a62021-12-02T18:51:45ZThe functional brain favours segregated modular connectivity at old age unless affected by neurodegeneration10.1038/s42003-021-02497-02399-3642https://doaj.org/article/3830c7bf2bbc4d73a4e49eaebe0f78a62021-08-01T00:00:00Zhttps://doi.org/10.1038/s42003-021-02497-0https://doaj.org/toc/2399-3642Chen at al used fMRI to study the brain connectivity in two ageing cohorts and a mixed cohort of patients with neurodegenerative diseases. They demonstrated that with ageing the brain moves towards a more segregated modular structure, however this is disrupted by neurodegenerative diseases.Xue ChenJoe NecusLuis R. PerazaRamtin MehraramYanjiang WangJohn T. O’BrienAndrew BlamireMarcus KaiserJohn-Paul TaylorNature PortfolioarticleBiology (General)QH301-705.5ENCommunications Biology, Vol 4, Iss 1, Pp 1-16 (2021)
institution DOAJ
collection DOAJ
language EN
topic Biology (General)
QH301-705.5
spellingShingle Biology (General)
QH301-705.5
Xue Chen
Joe Necus
Luis R. Peraza
Ramtin Mehraram
Yanjiang Wang
John T. O’Brien
Andrew Blamire
Marcus Kaiser
John-Paul Taylor
The functional brain favours segregated modular connectivity at old age unless affected by neurodegeneration
description Chen at al used fMRI to study the brain connectivity in two ageing cohorts and a mixed cohort of patients with neurodegenerative diseases. They demonstrated that with ageing the brain moves towards a more segregated modular structure, however this is disrupted by neurodegenerative diseases.
format article
author Xue Chen
Joe Necus
Luis R. Peraza
Ramtin Mehraram
Yanjiang Wang
John T. O’Brien
Andrew Blamire
Marcus Kaiser
John-Paul Taylor
author_facet Xue Chen
Joe Necus
Luis R. Peraza
Ramtin Mehraram
Yanjiang Wang
John T. O’Brien
Andrew Blamire
Marcus Kaiser
John-Paul Taylor
author_sort Xue Chen
title The functional brain favours segregated modular connectivity at old age unless affected by neurodegeneration
title_short The functional brain favours segregated modular connectivity at old age unless affected by neurodegeneration
title_full The functional brain favours segregated modular connectivity at old age unless affected by neurodegeneration
title_fullStr The functional brain favours segregated modular connectivity at old age unless affected by neurodegeneration
title_full_unstemmed The functional brain favours segregated modular connectivity at old age unless affected by neurodegeneration
title_sort functional brain favours segregated modular connectivity at old age unless affected by neurodegeneration
publisher Nature Portfolio
publishDate 2021
url https://doaj.org/article/3830c7bf2bbc4d73a4e49eaebe0f78a6
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