Colonization of dermal arterioles by Neisseria meningitidis provides a safe haven from neutrophils

The human pathogen Neisseria meningitidis colonizes blood vessels and causes vascular damage, despite a neutrophil-rich inflammatory infiltrate. Here, Manriquez et al. use a humanized mouse model to show that pathogen colonization of capillaries and arterioles creates an intravascular niche that pre...

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Autores principales:	Valeria Manriquez, Pierre Nivoit, Tomas Urbina, Hebert Echenique-Rivera, Keira Melican, Marie-Paule Fernandez-Gerlinger, Patricia Flamant, Taliah Schmitt, Patrick Bruneval, Dorian Obino, Guillaume Duménil
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2021
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/3831caa54fa047ecaa07a6a930b57045
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spelling	oai:doaj.org-article:3831caa54fa047ecaa07a6a930b570452021-12-02T16:13:56ZColonization of dermal arterioles by Neisseria meningitidis provides a safe haven from neutrophils10.1038/s41467-021-24797-z2041-1723https://doaj.org/article/3831caa54fa047ecaa07a6a930b570452021-07-01T00:00:00Zhttps://doi.org/10.1038/s41467-021-24797-zhttps://doaj.org/toc/2041-1723The human pathogen Neisseria meningitidis colonizes blood vessels and causes vascular damage, despite a neutrophil-rich inflammatory infiltrate. Here, Manriquez et al. use a humanized mouse model to show that pathogen colonization of capillaries and arterioles creates an intravascular niche that precludes an effective action of neutrophils.Valeria ManriquezPierre NivoitTomas UrbinaHebert Echenique-RiveraKeira MelicanMarie-Paule Fernandez-GerlingerPatricia FlamantTaliah SchmittPatrick BrunevalDorian ObinoGuillaume DuménilNature PortfolioarticleScienceQENNature Communications, Vol 12, Iss 1, Pp 1-15 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Valeria Manriquez Pierre Nivoit Tomas Urbina Hebert Echenique-Rivera Keira Melican Marie-Paule Fernandez-Gerlinger Patricia Flamant Taliah Schmitt Patrick Bruneval Dorian Obino Guillaume Duménil Colonization of dermal arterioles by Neisseria meningitidis provides a safe haven from neutrophils
description	The human pathogen Neisseria meningitidis colonizes blood vessels and causes vascular damage, despite a neutrophil-rich inflammatory infiltrate. Here, Manriquez et al. use a humanized mouse model to show that pathogen colonization of capillaries and arterioles creates an intravascular niche that precludes an effective action of neutrophils.
format	article
author	Valeria Manriquez Pierre Nivoit Tomas Urbina Hebert Echenique-Rivera Keira Melican Marie-Paule Fernandez-Gerlinger Patricia Flamant Taliah Schmitt Patrick Bruneval Dorian Obino Guillaume Duménil
author_facet	Valeria Manriquez Pierre Nivoit Tomas Urbina Hebert Echenique-Rivera Keira Melican Marie-Paule Fernandez-Gerlinger Patricia Flamant Taliah Schmitt Patrick Bruneval Dorian Obino Guillaume Duménil
author_sort	Valeria Manriquez
title	Colonization of dermal arterioles by Neisseria meningitidis provides a safe haven from neutrophils
title_short	Colonization of dermal arterioles by Neisseria meningitidis provides a safe haven from neutrophils
title_full	Colonization of dermal arterioles by Neisseria meningitidis provides a safe haven from neutrophils
title_fullStr	Colonization of dermal arterioles by Neisseria meningitidis provides a safe haven from neutrophils
title_full_unstemmed	Colonization of dermal arterioles by Neisseria meningitidis provides a safe haven from neutrophils
title_sort	colonization of dermal arterioles by neisseria meningitidis provides a safe haven from neutrophils
publisher	Nature Portfolio
publishDate	2021
url	https://doaj.org/article/3831caa54fa047ecaa07a6a930b57045
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Colonization of dermal arterioles by Neisseria meningitidis provides a safe haven from neutrophils

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