Structural and Biochemical Characterization of Poly-ADP-ribose Polymerase from Trypanosoma brucei
Abstract Trypanosoma brucei is a unicellular parasite responsible for African trypanosomiasis or sleeping sickness. It contains a single PARP enzyme opposed to many higher eukaryotes, which have numerous PARPs. PARPs are responsible for a post-translational modification, ADP-ribosylation, regulating...
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Main Authors: | Teemu Haikarainen, Mariana Schlesinger, Ezeogo Obaji, Silvia H. Fernández Villamil, Lari Lehtiö |
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Format: | article |
Language: | EN |
Published: |
Nature Portfolio
2017
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Online Access: | https://doaj.org/article/383567bfb60a4e1f9f36829cf9b4a8ca |
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