EVALUATION OF IMMUNE INDICES IN PATIENTS WITH INDOLENT AND AGGRESSIVE NON HODKIN`S LYMPHOMAS

Abstract. A survey of immunological indices in patients with non-Hodkin’s lymphomas was performed, including evaluation of lymphocyte subpopulations, functional activity of neutrophils, immunoglobulin levels in peripheral blood and cytokine concentrations in mononuclear blood cell cultures and blood...

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Autores principales: A. V. Yovdiy, V. I. Shardakov, T. P. Zagoskina, E. L. Nazarova, M. N. Khorobrykh
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Lenguaje:RU
Publicado: SPb RAACI 2014
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Acceso en línea:https://doaj.org/article/3843ca1b6bfa44a5af3ce8934d490d87
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spelling oai:doaj.org-article:3843ca1b6bfa44a5af3ce8934d490d872021-11-18T08:03:39ZEVALUATION OF IMMUNE INDICES IN PATIENTS WITH INDOLENT AND AGGRESSIVE NON HODKIN`S LYMPHOMAS1563-06252313-741X10.15789/1563-0625-2011-1-67-72https://doaj.org/article/3843ca1b6bfa44a5af3ce8934d490d872014-07-01T00:00:00Zhttps://www.mimmun.ru/mimmun/article/view/282https://doaj.org/toc/1563-0625https://doaj.org/toc/2313-741XAbstract. A survey of immunological indices in patients with non-Hodkin’s lymphomas was performed, including evaluation of lymphocyte subpopulations, functional activity of neutrophils, immunoglobulin levels in peripheral blood and cytokine concentrations in mononuclear blood cell cultures and blood serum. The study revealed depressed indices of cellular and humoral immunity, like as an imbalance in Th1/Th2 cytokine production. T cell immune deficiency in the patients with aggressive lymphomas was more expressed, being also combined with significant deviations in cytokine status, as compared to a group of patients with indolent lymphomas. (Med. Immunol., 2011, vol. 13, N 1, pp 67-72)A. V. YovdiyV. I. ShardakovT. P. ZagoskinaE. L. NazarovaM. N. KhorobrykhSPb RAACIarticlenon-hodgkin lymphomaimmune parameterscytokinesImmunologic diseases. AllergyRC581-607RUMedicinskaâ Immunologiâ, Vol 13, Iss 1, Pp 67-72 (2014)
institution DOAJ
collection DOAJ
language RU
topic non-hodgkin lymphoma
immune parameters
cytokines
Immunologic diseases. Allergy
RC581-607
spellingShingle non-hodgkin lymphoma
immune parameters
cytokines
Immunologic diseases. Allergy
RC581-607
A. V. Yovdiy
V. I. Shardakov
T. P. Zagoskina
E. L. Nazarova
M. N. Khorobrykh
EVALUATION OF IMMUNE INDICES IN PATIENTS WITH INDOLENT AND AGGRESSIVE NON HODKIN`S LYMPHOMAS
description Abstract. A survey of immunological indices in patients with non-Hodkin’s lymphomas was performed, including evaluation of lymphocyte subpopulations, functional activity of neutrophils, immunoglobulin levels in peripheral blood and cytokine concentrations in mononuclear blood cell cultures and blood serum. The study revealed depressed indices of cellular and humoral immunity, like as an imbalance in Th1/Th2 cytokine production. T cell immune deficiency in the patients with aggressive lymphomas was more expressed, being also combined with significant deviations in cytokine status, as compared to a group of patients with indolent lymphomas. (Med. Immunol., 2011, vol. 13, N 1, pp 67-72)
format article
author A. V. Yovdiy
V. I. Shardakov
T. P. Zagoskina
E. L. Nazarova
M. N. Khorobrykh
author_facet A. V. Yovdiy
V. I. Shardakov
T. P. Zagoskina
E. L. Nazarova
M. N. Khorobrykh
author_sort A. V. Yovdiy
title EVALUATION OF IMMUNE INDICES IN PATIENTS WITH INDOLENT AND AGGRESSIVE NON HODKIN`S LYMPHOMAS
title_short EVALUATION OF IMMUNE INDICES IN PATIENTS WITH INDOLENT AND AGGRESSIVE NON HODKIN`S LYMPHOMAS
title_full EVALUATION OF IMMUNE INDICES IN PATIENTS WITH INDOLENT AND AGGRESSIVE NON HODKIN`S LYMPHOMAS
title_fullStr EVALUATION OF IMMUNE INDICES IN PATIENTS WITH INDOLENT AND AGGRESSIVE NON HODKIN`S LYMPHOMAS
title_full_unstemmed EVALUATION OF IMMUNE INDICES IN PATIENTS WITH INDOLENT AND AGGRESSIVE NON HODKIN`S LYMPHOMAS
title_sort evaluation of immune indices in patients with indolent and aggressive non hodkin`s lymphomas
publisher SPb RAACI
publishDate 2014
url https://doaj.org/article/3843ca1b6bfa44a5af3ce8934d490d87
work_keys_str_mv AT avyovdiy evaluationofimmuneindicesinpatientswithindolentandaggressivenonhodkinslymphomas
AT vishardakov evaluationofimmuneindicesinpatientswithindolentandaggressivenonhodkinslymphomas
AT tpzagoskina evaluationofimmuneindicesinpatientswithindolentandaggressivenonhodkinslymphomas
AT elnazarova evaluationofimmuneindicesinpatientswithindolentandaggressivenonhodkinslymphomas
AT mnkhorobrykh evaluationofimmuneindicesinpatientswithindolentandaggressivenonhodkinslymphomas
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