STRAP regulates alternative splicing fidelity during lineage commitment of mouse embryonic stem cells
STRAP (serine threonine kinase receptor-associated protein) promotes tumorigenicity. Here the authors report that STRAP associates with spliceosome and regulates alternative splicing during embryonic stem cell lineage commitment and early mouse embryo organogenesis.
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Nature Portfolio
2020
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oai:doaj.org-article:384c3fe5ae0a46a19a739286b1d0d2572021-12-02T13:23:47ZSTRAP regulates alternative splicing fidelity during lineage commitment of mouse embryonic stem cells10.1038/s41467-020-19698-62041-1723https://doaj.org/article/384c3fe5ae0a46a19a739286b1d0d2572020-11-01T00:00:00Zhttps://doi.org/10.1038/s41467-020-19698-6https://doaj.org/toc/2041-1723STRAP (serine threonine kinase receptor-associated protein) promotes tumorigenicity. Here the authors report that STRAP associates with spliceosome and regulates alternative splicing during embryonic stem cell lineage commitment and early mouse embryo organogenesis.Lin JinYunjia ChenDavid K. CrossmanArunima DattaTrung VuJames A. MobleyMalay Kumar BasuMariangela ScarduzioHengbin WangChenbei ChangPran K. DattaNature PortfolioarticleScienceQENNature Communications, Vol 11, Iss 1, Pp 1-18 (2020) |
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Science Q Lin Jin Yunjia Chen David K. Crossman Arunima Datta Trung Vu James A. Mobley Malay Kumar Basu Mariangela Scarduzio Hengbin Wang Chenbei Chang Pran K. Datta STRAP regulates alternative splicing fidelity during lineage commitment of mouse embryonic stem cells |
description |
STRAP (serine threonine kinase receptor-associated protein) promotes tumorigenicity. Here the authors report that STRAP associates with spliceosome and regulates alternative splicing during embryonic stem cell lineage commitment and early mouse embryo organogenesis. |
format |
article |
author |
Lin Jin Yunjia Chen David K. Crossman Arunima Datta Trung Vu James A. Mobley Malay Kumar Basu Mariangela Scarduzio Hengbin Wang Chenbei Chang Pran K. Datta |
author_facet |
Lin Jin Yunjia Chen David K. Crossman Arunima Datta Trung Vu James A. Mobley Malay Kumar Basu Mariangela Scarduzio Hengbin Wang Chenbei Chang Pran K. Datta |
author_sort |
Lin Jin |
title |
STRAP regulates alternative splicing fidelity during lineage commitment of mouse embryonic stem cells |
title_short |
STRAP regulates alternative splicing fidelity during lineage commitment of mouse embryonic stem cells |
title_full |
STRAP regulates alternative splicing fidelity during lineage commitment of mouse embryonic stem cells |
title_fullStr |
STRAP regulates alternative splicing fidelity during lineage commitment of mouse embryonic stem cells |
title_full_unstemmed |
STRAP regulates alternative splicing fidelity during lineage commitment of mouse embryonic stem cells |
title_sort |
strap regulates alternative splicing fidelity during lineage commitment of mouse embryonic stem cells |
publisher |
Nature Portfolio |
publishDate |
2020 |
url |
https://doaj.org/article/384c3fe5ae0a46a19a739286b1d0d257 |
work_keys_str_mv |
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1718393142546268160 |