STRAP regulates alternative splicing fidelity during lineage commitment of mouse embryonic stem cells

STRAP (serine threonine kinase receptor-associated protein) promotes tumorigenicity. Here the authors report that STRAP associates with spliceosome and regulates alternative splicing during embryonic stem cell lineage commitment and early mouse embryo organogenesis.

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Autores principales: Lin Jin, Yunjia Chen, David K. Crossman, Arunima Datta, Trung Vu, James A. Mobley, Malay Kumar Basu, Mariangela Scarduzio, Hengbin Wang, Chenbei Chang, Pran K. Datta
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Lenguaje:EN
Publicado: Nature Portfolio 2020
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Acceso en línea:https://doaj.org/article/384c3fe5ae0a46a19a739286b1d0d257
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spelling oai:doaj.org-article:384c3fe5ae0a46a19a739286b1d0d2572021-12-02T13:23:47ZSTRAP regulates alternative splicing fidelity during lineage commitment of mouse embryonic stem cells10.1038/s41467-020-19698-62041-1723https://doaj.org/article/384c3fe5ae0a46a19a739286b1d0d2572020-11-01T00:00:00Zhttps://doi.org/10.1038/s41467-020-19698-6https://doaj.org/toc/2041-1723STRAP (serine threonine kinase receptor-associated protein) promotes tumorigenicity. Here the authors report that STRAP associates with spliceosome and regulates alternative splicing during embryonic stem cell lineage commitment and early mouse embryo organogenesis.Lin JinYunjia ChenDavid K. CrossmanArunima DattaTrung VuJames A. MobleyMalay Kumar BasuMariangela ScarduzioHengbin WangChenbei ChangPran K. DattaNature PortfolioarticleScienceQENNature Communications, Vol 11, Iss 1, Pp 1-18 (2020)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Lin Jin
Yunjia Chen
David K. Crossman
Arunima Datta
Trung Vu
James A. Mobley
Malay Kumar Basu
Mariangela Scarduzio
Hengbin Wang
Chenbei Chang
Pran K. Datta
STRAP regulates alternative splicing fidelity during lineage commitment of mouse embryonic stem cells
description STRAP (serine threonine kinase receptor-associated protein) promotes tumorigenicity. Here the authors report that STRAP associates with spliceosome and regulates alternative splicing during embryonic stem cell lineage commitment and early mouse embryo organogenesis.
format article
author Lin Jin
Yunjia Chen
David K. Crossman
Arunima Datta
Trung Vu
James A. Mobley
Malay Kumar Basu
Mariangela Scarduzio
Hengbin Wang
Chenbei Chang
Pran K. Datta
author_facet Lin Jin
Yunjia Chen
David K. Crossman
Arunima Datta
Trung Vu
James A. Mobley
Malay Kumar Basu
Mariangela Scarduzio
Hengbin Wang
Chenbei Chang
Pran K. Datta
author_sort Lin Jin
title STRAP regulates alternative splicing fidelity during lineage commitment of mouse embryonic stem cells
title_short STRAP regulates alternative splicing fidelity during lineage commitment of mouse embryonic stem cells
title_full STRAP regulates alternative splicing fidelity during lineage commitment of mouse embryonic stem cells
title_fullStr STRAP regulates alternative splicing fidelity during lineage commitment of mouse embryonic stem cells
title_full_unstemmed STRAP regulates alternative splicing fidelity during lineage commitment of mouse embryonic stem cells
title_sort strap regulates alternative splicing fidelity during lineage commitment of mouse embryonic stem cells
publisher Nature Portfolio
publishDate 2020
url https://doaj.org/article/384c3fe5ae0a46a19a739286b1d0d257
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