Polymerase-endonuclease amplification reaction (PEAR) for large-scale enzymatic production of antisense oligonucleotides.
Antisense oligonucleotides targeting microRNAs or their mRNA targets prove to be powerful tools for molecular biology research and may eventually emerge as new therapeutic agents. Synthetic oligonucleotides are often contaminated with highly homologous failure sequences. Synthesis of a certain oligo...
Guardado en:
Autores principales: | Xiaolong Wang, Deming Gou, Shuang-yong Xu |
---|---|
Formato: | article |
Lenguaje: | EN |
Publicado: |
Public Library of Science (PLoS)
2010
|
Materias: | |
Acceso en línea: | https://doaj.org/article/384c7d9c97bf43b6bb50c1092c81b81b |
Etiquetas: |
Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!
|
Ejemplares similares
-
Recombinase Polymerase Amplification Assay with and without Nuclease-Dependent-Labeled Oligonucleotide Probe
por: Aleksandr V. Ivanov, et al.
Publicado: (2021) -
Phospholamban antisense oligonucleotides improve cardiac function in murine cardiomyopathy
por: Niels Grote Beverborg, et al.
Publicado: (2021) -
Tritium labeling of antisense oligonucleotides via different conjugation agents
por: Martin R. Edelmann, et al.
Publicado: (2021) -
Induction of cryptic pre-mRNA splice-switching by antisense oligonucleotides
por: Kristin A. Ham, et al.
Publicado: (2021) -
Antisense oligonucleotide modulation of non-productive alternative splicing upregulates gene expression
por: Kian Huat Lim, et al.
Publicado: (2020)